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Tmem60 Gene Detail
Summary
  • Symbol
    Tmem60
  • Name
    transmembrane protein 60
  • Synonyms
    MGC:38035
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673965
    NCBI Gene: 212090
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:21087451-21091868 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 9.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673965
 protein coding gene Chr5:21087189-21091868 (+)
129S1/SvImJ ENSMUSG00200010402
 protein coding gene Chr5:16723902-16728581 (+)
A/J ENSMUSG00195039235
 protein coding gene Chr5:16200339-16205018 (+)
AKR/J ENSMUSG00220035281
 protein coding gene Chr5:16240379-16245060 (+)
BALB/cJ ENSMUSG00180022902
 protein coding gene Chr5:16052286-16056965 (+)
C3H/HeJ ENSMUSG00175026752
 protein coding gene Chr5:18009096-18013775 (+)
C57BL/6NJ ENSMUSG00215012588
 protein coding gene Chr5:16619839-16624518 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026980
 protein coding gene Chr5:15892798-15897179 (+)
CAST/EiJ ENSTCUG00005003331
 protein coding gene Chr5:16293533-16298221 (+)
CBA/J ENSMUSG00210004823
 protein coding gene Chr5:17043253-17047932 (+)
DBA/2J ENSMUSG00185016470
 protein coding gene Chr5:18539796-18544475 (+)
FVB/NJ ENSMUSG00205020176
 protein coding gene Chr5:15751180-15755859 (+)
JF1/MsJ ENSUMUG00000004656
 protein coding gene Chr5:23143013-23147720 (+)
LP/J ENSMUSG00230023437
 protein coding gene Chr5:23006260-23010939 (+)
NOD/ShiLtJ ENSMUSG00190004439
 protein coding gene Chr5:16068071-16072750 (+)
NZO/HlLtJ ENSMUSG00225008402
 protein coding gene Chr5:28402082-28406762 (+)
PWK/PhJ ENSLUMG00010034762
 protein coding gene Chr5:16173222-16177900 (+)
SPRET/EiJ ENSMSPG00010027124
 protein coding gene Chr5:17054787-17059487 (+)
WSB/EiJ ENSIUOG00005031337
 protein coding gene Chr5:18868892-18873573 (+)



Homology
more
  • Human Ortholog
    TMEM60, transmembrane protein 60
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM60, transmembrane protein 60
  • Synonyms
    C7orf35, DC32
  • Links
    NCBI Gene ID: 85025
    UniProt: Q9H2L4

  • Chr Location
    7q11.23; chr7:77793728-77799484 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 212090 NCBI Gene Model | MGI Sequence Detail 4418 C57BL/6J ±  kb
    transcript NM_177601 RefSeq | MGI Sequence Detail 899 C57BL/6  
    polypeptide Q8K174 UniProt | EBI | MGI Sequence Detail 133 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 2
    References
    more
    • Summaries
      All 37
      Diseases 1
      Gene Ontology 1
      Phenotypes 19
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory