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Gpr75 Gene Detail
Summary
  • Symbol
    Gpr75
  • Name
    G protein-coupled receptor 75
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441843
    NCBI Gene: 237716
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:30835358-30843729 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 18.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441843
 protein coding gene Chr11:30834636-30846090 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018117
 protein coding gene Chr11:29000776-29009773 (+)
A/J MGP_AJ_G0018090
 protein coding gene Chr11:27919597-27927712 (+)
AKR/J MGP_AKRJ_G0018054
 protein coding gene Chr11:28804792-28815158 (+)
BALB/cJ MGP_BALBcJ_G0018059
 protein coding gene Chr11:28124258-28132313 (+)
C3H/HeJ MGP_C3HHeJ_G0017872
 protein coding gene Chr11:28739703-28748611 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018510
 protein coding gene Chr11:29958879-29968189 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016167
 protein coding gene Chr11:26439082-26447217 (+)
CAST/EiJ MGP_CASTEiJ_G0017434
 protein coding gene Chr11:28828283-28836333 (+)
CBA/J MGP_CBAJ_G0017845
 protein coding gene Chr11:31402382-31414350 (+)
DBA/2J MGP_DBA2J_G0017955
 protein coding gene Chr11:27736833-27745063 (+)
FVB/NJ MGP_FVBNJ_G0017949
 protein coding gene Chr11:27531236-27539144 (+)
LP/J MGP_LPJ_G0018027
 protein coding gene Chr11:29244756-29252963 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017973
 protein coding gene Chr11:32460114-32468453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018551
 protein coding gene Chr11:28903169-28913382 (+)
PWK/PhJ MGP_PWKPhJ_G0017216
 protein coding gene Chr11:27836164-27844760 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017010
 protein coding gene Chr11:28616981-28625092 (+)
WSB/EiJ MGP_WSBEiJ_G0017486
 protein coding gene Chr11:28591655-28601316 (+)



Homology
more
  • Human Ortholog
    GPR75, G protein-coupled receptor 75
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR75, G protein-coupled receptor 75
  • Synonyms
    GPRchr2, WI31133
  • Links
    NCBI Gene ID: 10936
    neXtProt AC: NX_O95800
    UniProt: O95800

  • Chr Location
    2p16.2; chr2:53852913-53860033 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    767
  • Tissues
    61
  • cDNA Data
    5
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043999 Ensembl Gene Model | MGI Sequence Detail 8372 C57BL/6J ±  kb
transcript ENSMUST00000109430 Ensembl | MGI Sequence Detail 2926 Not Applicable  
polypeptide ENSMUSP00000105057 Ensembl | MGI Sequence Detail 540 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:323812 Akbari P, et al., Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity. Science. 2021 Jul 2;373(6550)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/24/2023
MGI 6.22 		The Jackson Laboratory