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Myocd Gene Detail
Summary
  • Symbol
    Myocd
  • Name
    myocardin
  • Synonyms
    Srfcp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137495
    NCBI Gene: 214384
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:65067387-65160815 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 40.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2964 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137495
 protein coding gene Chr11:65064434-65160821 (-)
129S1/SvImJ ENSMUSG00200043743
 protein coding gene Chr11:61991104-62084240 (-)
A/J ENSMUSG00195037914
 protein coding gene Chr11:62033318-62126782 (-)
AKR/J ENSMUSG00220042944
 protein coding gene Chr11:62145354-62238504 (-)
BALB/cJ ENSMUSG00180052896
 protein coding gene Chr11:62073990-62167146 (-)
C3H/HeJ ENSMUSG00175040869
 protein coding gene Chr11:62049793-62143262 (-)
C57BL/6NJ ENSMUSG00215054956
 protein coding gene Chr11:61832680-61926125 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016512
 protein coding gene Chr11:59958353-60057252 (-)
CAST/EiJ ENSTCUG00005037793
 protein coding gene Chr11:61609641-61704298 (-)
CBA/J ENSMUSG00210051571
 protein coding gene Chr11:61879424-61972562 (-)
DBA/2J ENSMUSG00185056610
 protein coding gene Chr11:62073544-62166702 (-)
FVB/NJ ENSMUSG00205034445
 protein coding gene Chr11:61958010-62059420 (-)
JF1/MsJ ENSUMUG00000021793
 protein coding gene Chr11:62476195-62570472 (-)
LP/J ENSMUSG00230052716
 protein coding gene Chr11:63212146-63305276 (-)
NOD/ShiLtJ ENSMUSG00190053557
 protein coding gene Chr11:62081717-62181515 (-)
NZO/HlLtJ ENSMUSG00225043438
 protein coding gene Chr11:65386866-65486469 (-)
PWK/PhJ ENSLUMG00010037284
 protein coding gene Chr11:61999841-62093973 (-)
SPRET/EiJ ENSMSPG00010044869
 protein coding gene Chr11:62699339-62792603 (-)
WSB/EiJ ENSIUOG00005048967
 protein coding gene Chr11:61994182-62087550 (-)



Homology
more
  • Human Ortholog
    MYOCD, myocardin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYOCD, myocardin
  • Synonyms
    MGBL, MYCD
  • Links
    NCBI Gene ID: 93649
    UniProt: Q8IZQ8

  • Chr Location
    17p12; chr17:12665890-12768949 (+)  GRCh38
Human Diseases
more
  • Diseases
    3 with Myocd mouse models; 1 with human MYOCD associations

Human Disease Mouse Models
      
IDs
 View 2 models
      
IDs
 View 2 models
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    3 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    37 phenotypes from 6 alleles in 9 genetic backgrounds
    4 phenotypes from multigenic genotypes
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    117
  • GO References
    32
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    828
  • Tissues
    119
  • cDNA Data
    17
  • Literature Summary
    91
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020542 Ensembl Gene Model | MGI Sequence Detail 93429 C57BL/6J ±  kb
    transcript ENSMUST00000108695 Ensembl | MGI Sequence Detail 5114 Not Applicable  
    polypeptide ENSMUSP00000104335 Ensembl | MGI Sequence Detail 983 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      Genomic 2
      cDNA 17
      Primer pair 20
      Other 6

      Microarray probesets 4
    References
    more
    • Summaries
      All 186
      Developmental Gene Expression 91
      Diseases 3
      Gene Ontology 32
      Phenotypes 31
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:390120 Trowe MO, et al., Mesenchymal WNT signaling coordinates epithelial and mesenchymal differentiation in the developing murine ureter. Cell Commun Signal. 2026 Jul 21;24(1)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory