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Hdgfl1 Gene Detail
Summary
  • Symbol
    Hdgfl1
  • Name
    HDGF like 1
  • Synonyms
    Hdgfrp1, HRP-1, Pwwp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194493
    NCBI Gene: 15192
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:26952156-26954148 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.09 cM, cytoband A3.3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194493
 protein coding gene Chr13:26952155-26954148 (-)
129S1/SvImJ ENSMUSG00200028359
 protein coding gene Chr13:24111797-24113795 (-)
A/J ENSMUSG00195037843
 protein coding gene Chr13:23249925-23251918 (-)
AKR/J ENSMUSG00220012940
 protein coding gene Chr13:23060470-23062463 (-)
BALB/cJ ENSMUSG00180020471
 protein coding gene Chr13:23555191-23557182 (-)
C3H/HeJ ENSMUSG00175028938
 protein coding gene Chr13:23577917-23579909 (-)
C57BL/6NJ ENSMUSG00215007272
 protein coding gene Chr13:23716861-23718853 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018361
 protein coding gene Chr13:22504022-22505968 (-)
CAST/EiJ ENSTCUG00005010024
 protein coding gene Chr13:23747307-23749308 (-)
CBA/J ENSMUSG00210026629
 protein coding gene Chr13:23522578-23524570 (-)
DBA/2J ENSMUSG00185020431
 protein coding gene Chr13:24344128-24346120 (-)
FVB/NJ ENSMUSG00205020542
 protein coding gene Chr13:23343505-23345498 (-)
JF1/MsJ ENSUMUG00000014025
 protein coding gene Chr13:24001691-24003678 (-)
LP/J ENSMUSG00230016681
 protein coding gene Chr13:33665536-33667528 (-)
NOD/ShiLtJ ENSMUSG00190029993
 protein coding gene Chr13:23326239-23328231 (-)
NZO/HlLtJ ENSMUSG00225045429
 protein coding gene Chr13:27451732-27453724 (-)
PWK/PhJ ENSLUMG00010029060
 protein coding gene Chr13:22847802-22849789 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005016100
 protein coding gene Chr13:22888896-22890985 (-)



Homology
more
  • Human Ortholog
    HDGFL1, HDGF like 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HDGFL1, HDGF like 1
  • Synonyms
    dJ309H15.1, Hdgfrp1, HRP-1, PWWP1
  • Links
    NCBI Gene ID: 154150
    UniProt: Q5TGJ6

  • Chr Location
    6p22.3; chr6:22569566-22571666 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice exhibit normal male fertility.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    654
  • Tissues
    6
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045835 Ensembl Gene Model | MGI Sequence Detail 1993 C57BL/6J ±  kb
    transcript ENSMUST00000055915 Ensembl | MGI Sequence Detail 1993 Not Applicable  
    polypeptide ENSMUSP00000057557 Ensembl | MGI Sequence Detail 283 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR000313 PWWP domain
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 6
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Phenotypes 14
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory