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Phenotype Images associated with this Gene
Symbol
Name
ID 		Tbx1
T-box 1
MGI:98493


11 phenotype image(s) for Tbx1 alleles
Showing image(s) 1 to 10 		Show   figures per page Next Last
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Caption: Thymic aplasia, nasal malformations, and eye, pharyngeal and ear defects in Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+ Foxg1tm1(cre)Skm/Foxg1+ mice and microcephaly, ocular and ear defects in Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+ Tg(Pax2-cre)1Akg/0 mice (details)
Represented Alleles:
Foxg1tm1(cre)Skm, forkhead box G1; targeted mutation 1, Susan K McConnell
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem, gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tg(Pax2-cre)1Akg, transgene insertion 1, Andrew K Groves
Copyright: This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435
Caption: Altered cell adhesion properties in Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+ Tg(Pax2-cre)1Akg/0 mice (details)
Represented Alleles:
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem, gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tg(Pax2-cre)1Akg, transgene insertion 1, Andrew K Groves
Copyright: This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435
Caption: Failure of inner ear morphogenesis in Tbx1tm1Bld/Tbx1tm1Bld mice at E14.5 and partial rescue of inner ear morphogenesis in Tbx1tm6(cre)Bld/Tbx1tm1Bld Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/ Gt(ROSA)26Sor+ mice (details)
Represented Alleles:
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem, gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tbx1tm1Bld, T-box 1; targeted mutation 1, Antonio Baldini
Tbx1tm6(cre)Bld, T-box 1; targeted mutation 6, Antonio Baldini
Copyright: This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435
Caption: Heart development defects in Tbx1tm6(cre)Bld/Tbx1+ Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem mice (details)
Represented Alleles:
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem, gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tbx1tm6(cre)Bld, T-box 1; targeted mutation 6, Antonio Baldini
Copyright: This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435
Caption: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem can patially rescue heart phenotypes in Tbx1tm6(cre)Bld/Tbx1tm1Bld mice (details)
Represented Alleles:
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem, gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tbx1tm1Bld, T-box 1; targeted mutation 1, Antonio Baldini
Tbx1tm6(cre)Bld, T-box 1; targeted mutation 6, Antonio Baldini
Copyright: This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435
Caption: Hypoplastic outflow tract cushions in Six1tm1Mair/Six1tm1Mair Eya1tm1Rilm/Eya1tm1Rilm mice (details)
Represented Alleles:
Eya1tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas
Six1tm1Mair, sine oculis-related homeobox 1; targeted mutation 1, Pascal Maire
Tbx1tm1Bem, T-box 1; targeted mutation 1, Bernice E Morrow
Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
Caption: Cardiovascular defects in mice with mutations of one or both copies of Eya1tm1Rilm and Tbx1tm1Bem (details)
Represented Alleles:
Eya1tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas
Tbx1tm1Bem, T-box 1; targeted mutation 1, Bernice E Morrow
Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
Caption: Pharyngeal arch artery patterning defects in Chd7Whi/Chd7+, Chd7Gt(XK403)Byg/Chd7+ and Chd7Gt(XK403)Byg/Chd7+ Tbx1tm1Bld/Tbx1+ embryos (details)
Represented Alleles:
Chd7Gt(XK403)Byg, chromodomain helicase DNA binding protein 7; gene trap XK403, BayGenomics
Chd7Whi, chromodomain helicase DNA binding protein 7; whirligig
Tbx1tm1Bld, T-box 1; targeted mutation 1, Antonio Baldini
Copyright: This image is from Randall V, J Clin Invest 2009 Nov;119(11):3301-10 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:154590
Caption: Malformations of the semicircular canals in Chd7Whi/Chd7+, Tbx1tm1Bld/Tbx1+, and Chd7Whi/Chd7+ Tbx1tm1Bld/Tbx1+ mice (details)
Represented Alleles:
Chd7Whi, chromodomain helicase DNA binding protein 7; whirligig
Tbx1tm1Bld, T-box 1; targeted mutation 1, Antonio Baldini
Copyright: This image is from Randall V, J Clin Invest 2009 Nov;119(11):3301-10 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:154590
Caption: Fourth pharyngeal arch artery aplasia in Tbx1tm2.1Bem/Tbx1+ Tfap2atm1(cre)Moon/Tfap2a+ mice (details)
Represented Alleles:
Tbx1tm2.1Bem, T-box 1; targeted mutation 2.1, Bernice E Morrow
Tfap2atm1(cre)Moon, transcription factor AP-2, alpha; targeted mutation 1, Anne M Moon
Copyright: This image is from Randall V, J Clin Invest 2009 Nov;119(11):3301-10 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:154590
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory