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Symbol Name ID |
Prnp
prion protein MGI:97769 |
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Caption: Neuropathologic processes of Prnptm3Lnq/Prnptm3Lnq mice
(details)
Represented Alleles:
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Activation of cell cycle and death markers in Prnptm3Lnq/Prnptm3Lnq (B and E), and Prnptm2Lnq/Prnptm2Lnq (C and F) brains
(details)
Represented Alleles:
Prnptm2Lnq,
prion protein; targeted mutation 2, Susan Lindquist
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Reactive gliosis in Prnptm3Lnq/Prnptm3Lnq (CJD) brain and neurodegeneration and dilated ventricles in Prnptm2Lnq/Prnptm2Lnq (FFI) brain
(details)
Represented Alleles:
Prnptm2Lnq,
prion protein; targeted mutation 2, Susan Lindquist
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Prion protein aggregates are present in the outer plexiform layer of Prnptm3Lnq/Prnptm3Lnq retina
(details)
Represented Alleles:
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Proteinase K resistant prion protein and prion protein aggregates in Prnptm2Lnq/Prnptm2Lnq and Prnptm3Lnq/Prnptm3Lnq brains
(details)
Represented Alleles:
Prnptm2Lnq,
prion protein; targeted mutation 2, Susan Lindquist
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Activation of cell cycle and death markers in Prnptm3Lnq/Prnptm3Lnq (CJD), and Prnptm2Lnq/Prnptm2Lnq (FFI) mice
(details)
Represented Alleles:
Prnptm2Lnq,
prion protein; targeted mutation 2, Susan Lindquist
Prnptm3Lnq,
prion protein; targeted mutation 3, Susan Lindquist
Copyright: This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A.
J:200974
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Caption: Tg(Prnp*S170N*N174T)1020Aag/0 Prnptm1Cwe/Prnptm1Cwe mice develop a lethal neurologic disease with lesions in the brain and muscle
(details)
Represented Alleles:
Prnptm1Cwe,
prion protein; targeted mutation 1, Charles Weissmann
Tg(Prnp)a20Cwe,
transgene insertion a20, Charles Weissmann
Tg(Prnp*S170N*N174T)1020Aag,
transgene insertion 1020, Adriano Aguzzi
Copyright: This image is from Sigurdson CJ, Proc Natl Acad Sci U S A 2009 Jan 6;106(1):304-9. Copyright 2009 National Academy of Sciences, U.S.A.
J:143528
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Caption: Ataxia, with circling movements and dargging of feet, in Tg(Prnp*S170N*N174T)1020Aag/0 Prnptm1Cwe/Prnptm1Cwe mice.
(details)
Represented Alleles:
Prnptm1Cwe,
prion protein; targeted mutation 1, Charles Weissmann
Tg(Prnp)a20Cwe,
transgene insertion a20, Charles Weissmann
Tg(Prnp*S170N*N174T)1020Aag,
transgene insertion 1020, Adriano Aguzzi
Copyright: This image is from Sigurdson CJ, Proc Natl Acad Sci U S A 2009 Jan 6;106(1):304-9. Copyright 2009 National Academy of Sciences, U.S.A.
J:143528
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Caption: Severe demyelinating lesions in Tg(Prnp*S170N*N174T)1020Aag/0 Prnptm1Cwe/Prnptm1Cwe mice
(details)
Represented Alleles:
Prnptm1Cwe,
prion protein; targeted mutation 1, Charles Weissmann
Tg(Prnp*S170N*N174T)1020Aag,
transgene insertion 1020, Adriano Aguzzi
Copyright: This image is from Sigurdson CJ, Proc Natl Acad Sci U S A 2009 Jan 6;106(1):304-9. Copyright 2009 National Academy of Sciences, U.S.A.
J:143528
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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