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Phenotype Image Detail
Image
Caption In the retina of Prnptm3Lnq/Prnptm3Lnq mice, prion protein (PrP) aggregates are present in the outer plexiform layer (Upper, arrows), containing the neuropil of the rods and cones, which appear to be degenerating in the H&E stain (Lower, arrows).
Copyright This image is from Jackson WS, Proc Natl Acad Sci U S A 2013 Sep 3;110(36):14759-64. Copyright 2013 National Academy of Sciences, U.S.A. J:200974
Associated
Alleles
Symbol Name
Prnptm3Lnq prion protein; targeted mutation 3, Susan Lindquist
Associated
Genotypes
Allelic Composition Genetic Background
Prnptm3Lnq/Prnptm3Lnq involves: 129P2/OlaHsd * C57BL/6N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory