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Phenotype Images associated with this Gene
Symbol
Name
ID 		Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680


7 phenotype image(s) for Kras alleles
Showing image(s) 1 to 7
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Click on allele symbol for full phenotype details.

Caption: Liver histology in mice with heterozygous and homozygous Fbxw7tm1.1Iken mutations in combination with an oncogenic KrasG12D mutation (details)
Represented Alleles:
Fbxw7tm1Iken, F-box and WD-40 domain protein 7; targeted mutation 1, Tsuneo Ikenoue
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Ikenoue T, Sci Rep 2018 Jan 31;8(1):2021, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:258194
Caption: Pancreatic tumors in Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 and Krastm4Tyj/Krastm4Tyj Cdkn2atm4Rdp/Cdkn2atm4Rdp Tg(Pdx1-cre)89.1Dam/0 mice (details)
Represented Alleles:
Cdkn2atm4Rdp, cyclin dependent kinase inhibitor 2A; targeted mutation 4, Ronald DePinho
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton
Trim33tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson
Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
Caption: Accelerated pancreatic neoplasia in Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 mice compared to Krastm4Tyj/Krastm4Tyj Tg(Pdx1-cre)89.1Dam/0 mice (details)
Represented Alleles:
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton
Trim33tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson
Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
Caption: Endocrine and exocrine compartments destruction in the pancreas of Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 mice (details)
Represented Alleles:
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton
Trim33tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson
Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
Caption: Presence of inflammatory cells in the pancreas associated with the cystic structures of Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 mice (details)
Represented Alleles:
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton
Trim33tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson
Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
Caption: Histology and immunophenotyping of mammary carcinomas in Eef1a1tm1(Kras*)Arge/Eef1a1+ Waptm1(cre)Arge/Wap+ mice (details)
Represented Alleles:
Eef1a1tm1(Kras*)Arge, eukaryotic translation elongation factor 1 alpha 1; targeted mutation 1, Argiris Efstratiadis
Waptm1(cre)Arge, whey acidic protein; targeted mutation 1, Argiris Efstratiadis
Copyright: This image is from Klinakis A, Proc Natl Acad Sci U S A 2009 Feb 17;106(7):2359-64. Copyright 2009 National Academy of Sciences, U.S.A. J:146290
Caption: Drug treatment of mammary carcinomas in Eef1a1tm1(Kras*)Arge/Eef1a1+ Waptm1(cre)Arge/Wap+ mice (details)
Represented Alleles:
Eef1a1tm1(Kras*)Arge, eukaryotic translation elongation factor 1 alpha 1; targeted mutation 1, Argiris Efstratiadis
Waptm1(cre)Arge, whey acidic protein; targeted mutation 1, Argiris Efstratiadis
Copyright: This image is from Klinakis A, Proc Natl Acad Sci U S A 2009 Feb 17;106(7):2359-64. Copyright 2009 National Academy of Sciences, U.S.A. J:146290
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory