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Symbol Name ID |
Chp1
calcineurin-like EF hand protein 1 MGI:1927185 |
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Caption: Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp embryos are developmentally delayed, show abnormal allantois and fragile allantois attachment, impaired embryo turning, abnormal head shape with failed cranial neural tube closure, abnormal heart development, and yolk sac defects.
(details)
Represented Alleles:
Chp1em1(IMPC)Tcp,
calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp placenta shows a diminished spongiotrophoblast layer, impaired chorioallantoic attachment, multiple labyrinth zone defects, and impaired chorioallantoic branching.
(details)
Represented Alleles:
Chp1em1(IMPC)Tcp,
calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp embryos show delayed development at E8.5.
(details)
Represented Alleles:
Chp1em1(IMPC)Tcp,
calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: By E9.5, AlleleSymbol(MGI:6388376|0)/Chp1em1(IMPC)Tcp embryos are all severely dysmorphic and smaller despite normal neural tube patterning and presence of all 3 germ layers.
(details)
Represented Alleles:
Chp1em1(IMPC)Tcp,
calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: E7.5 AlleleSymbol(MGI:6388376|0)/Chp1em1(IMPC)Tcp embryos are always the smallest embryos in the litter.
(details)
Represented Alleles:
Chp1em1(IMPC)Tcp,
calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/06/2026 MGI 6.24 |
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