Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Chp1^em1(IMPC)Tcp
Name:	calcineurin-like EF hand protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI ID:	MGI:6388376
Synonyms:	Chp1^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp embryos are developmentally delayed, show abnormal allantois and fragile allantois attachment, impaired embryo turning, abnormal head shape with failed cranial neural tube closure, abnormal heart development, and yolk sac defects.	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp	C57BL/6NCrl-Chp1^em1(IMPC)Tcp/TcpMmucd
	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp placenta shows a diminished spongiotrophoblast layer, impaired chorioallantoic attachment, multiple labyrinth zone defects, and impaired chorioallantoic branching.	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp	C57BL/6NCrl-Chp1^em1(IMPC)Tcp/TcpMmucd
	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp embryos show delayed development at E8.5.	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp	C57BL/6NCrl-Chp1^em1(IMPC)Tcp/TcpMmucd
	By E9.5, AlleleSymbol(MGI:6388376\|0)/Chp1^em1(IMPC)Tcp embryos are all severely dysmorphic and smaller despite normal neural tube patterning and presence of all 3 germ layers.	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp	C57BL/6NCrl-Chp1^em1(IMPC)Tcp/TcpMmucd
	E7.5 AlleleSymbol(MGI:6388376\|0)/Chp1^em1(IMPC)Tcp embryos are always the smallest embryos in the litter.	Chp1^em1(IMPC)Tcp/Chp1^em1(IMPC)Tcp	C57BL/6NCrl-Chp1^em1(IMPC)Tcp/TcpMmucd

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