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Phenotype Images associated with this Allele
Nomenclature
Symbol: Alg3em1(IMPC)J
Name: ALG3 alpha-1,3- mannosyltransferase; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6194900
Synonyms: Alg3-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Alg3em1(IMPC)J/Alg3em1(IMPC)J (-/-) embryos are smaller by E9.5 and and show developmental delay by E10.5, with abnormal head shape, and cardiac defects.Alg3em1(IMPC)J/Alg3em1(IMPC)JC57BL/6NJ-Alg3em1(IMPC)J/Mmjax
Placental defects in Alg3em1(IMPC)J/Alg3em1(IMPC)J embryosAlg3em1(IMPC)J/Alg3em1(IMPC)JC57BL/6NJ-Alg3em1(IMPC)J/Mmjax
E9.5 Alg3em1(IMPC)J/Alg3em1(IMPC)J (-/-) embryos exhibit normal germ layer patterning.Alg3em1(IMPC)J/Alg3em1(IMPC)JC57BL/6NJ-Alg3em1(IMPC)J/Mmjax
E10.5 Alg3em1(IMPC)J/Alg3em1(IMPC)J (-/-) embryos are smaller and the loose mesenchyme surrounding the neural tube appears less dense.Alg3em1(IMPC)J/Alg3em1(IMPC)JC57BL/6NJ-Alg3em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory