Phenotype Image Detail

Image

Caption

Alg3^em1(IMPC)J/Alg3^em1(IMPC)J (-/-) embryos are normal at E8.5. By E9.5 they are sometimes smaller and a minority display abnormal tail placement or shortened tails, although overall are difficult to discern from their litter mates. By E10.5 the homozygous mutants are apparent and are delayed with abnormal head shape, particularly the forebrain. Many have cardiac defects and abnormal blood pooling in head and heart. All mutants are dying by E11.5.

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Associated Alleles

Symbol	Name
Alg3^em1(IMPC)J	ALG3 alpha-1,3- mannosyltransferase; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Alg3^em1(IMPC)J/Alg3^em1(IMPC)J	C57BL/6NJ-Alg3^em1(IMPC)J/Mmjax