Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Tedc2^em1(IMPC)J
Name:	tubulin epsilon and delta complex 2; endonuclease-mediated mutation 1, Jackson
MGI ID:	MGI:6157624
Synonyms:	Tedc2^-

Images for
Allele

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Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J (-/-) embryonic phenotypes include failure to turn, kinked caudal neural tube, laterally splayed and open cranial neural tube, abnormal head and heart shape and cardiac edema.	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J	C57BL/6NJ-Tedc2^em1(IMPC)J/Mmjax
	At E9.5, Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J -/- placentas are properly developed and comparable to controls.	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J	C57BL/6NJ-Tedc2^em1(IMPC)J/Mmjax
	All E8.5 Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J embryos lack an appropriately patterned ventral neural tube, the notochord is absent in portions of the embryo and when it is absent, the gut tube is abnormally proximal to the neural tube.	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J	C57BL/6NJ-Tedc2^em1(IMPC)J/Mmjax
	By E9.5, all Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J (Tedc2-/-) embryos lack an appropriately patterned ventral neural tube. This mutant embryo has also failed to close the cranial neural tube.	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J	C57BL/6NJ-Tedc2^em1(IMPC)J/Mmjax
	In some E8.5 Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J (-/-) embryos, the notochord is absent.	Tedc2^em1(IMPC)J/Tedc2^em1(IMPC)J	C57BL/6NJ-Tedc2^em1(IMPC)J/Mmjax

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