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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ikbkgtm1.1Chtr
Name: inhibitor of kappaB kinase gamma; targeted mutation 1.1, Christian Trautwein
MGI ID: MGI:4355682
Synonyms: NemoFl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 livers are protected against Fas-mediated acute hepatic failureIkbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 mice are protected from anti-Fas mAb stimulated development of hepatitisIkbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 mice are sensitive to low doses of TRAIL-mediated liver injuryIkbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N
ConA promotes stronger liver damage in Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 mice than controls
Inflammation and steatohepatitis in 12 week old Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr Tg(Alb1-cre)7Gsc/0 and Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 miceIkbkgtm1.1Chtr/Ikbkgtm1.1Chtr
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N
Hepatocellular carcinoma in Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr Tg(Alb1-cre)7Gsc/0 and Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 miceIkbkgtm1.1Chtr/Ikbkgtm1.1Chtr
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N * SJL
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N
Ikbkgtm1.1Chtr/Y
Tnfrsf10btm1Wsed/Tnfrsf10btm1Wsed
Tg(Alb1-cre)7Gsc/0		involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Ikbkgtm1.1Chtr/Y
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tg(Alb1-cre)7Gsc/0		involves: C57BL/6 * FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory