Phenotype Image Detail

Image

Caption

Hepatocyte-specific Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 (NEMO^deltahepa) mice are protected against Fas-mediated acute hepatic failure. Macroscopic view of livers 3 hours after stimulation with an anti-Fas mAb (Jo2), and liver weight/body weight ratio in normal and mutant mice.

Copyright

This image is from Beraza N, J Exp Med 2009 Aug 3;206(8):1727-37, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:151485

Associated Alleles

Symbol	Name
Ikbkg^tm1.1Chtr	inhibitor of kappaB kinase gamma; targeted mutation 1.1, Christian Trautwein
Tg(Alb1-cre)7Gsc	transgene insertion 7, Gunther Schutz

Associated Genotypes

Allelic Composition	Genetic Background
Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0	involves: C57BL/6 * FVB/N * SJL