Gene Expression Image Detail

Reference

Figure

ID

J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382

S4

MGI:8350574

Image

Caption

(A) Compressed Z stack images of immunostaining, overlaid with 3D surface reconstruction of MUC1+ lumens, of WT and Lats1/2 pancreata at E11.5, E12.0, and E12.5 with insets showing higher magnification images of slice views (Imaris) through the epithelium and apical lumen. (C,E) Immunostaining of sections of wild type and Lats1/2^PanKO pancreata. (C) Higher magnification views of pancreatic cap cells are shown in the second row, with the pancreatic edge outlined in white. Magnified views of pancreatic body cells are shown in the third row. Apical and basal cell borders are illustrated with yellow and red outlines, respectively. Scale = 50 um (A,C,E).

Copyright

This image is from Braitsch CM, PLoS Biol 2019 Jul;17(7):e3000382, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A WT E11.5	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
A WT E12.0	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
A WT E12.5	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
A Lats1/2^PanKO E11.5	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
A Lats1/2^PanKO E12.0	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
A Lats1/2^PanKO E12.5	MGI:8346384 (Cdh1) MGI:8346383 (Muc1)
C WT row 1	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
C WT row 2	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
C WT row 3	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
C Lats1/2^PanKO row 1	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
C Lats1/2^PanKO row 2	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
C Lats1/2^PanKO row 3	MGI:8351284 (Ctnnb1) MGI:8352276 (Golga2) MGI:8352277 (Prkci)
B	MGI:8352274 (Muc1)
E WT upper	MGI:8351675 (Lamc1) MGI:8346383 (Muc1) MGI:8352275 (Myl2)
E WT lower	MGI:8351675 (Lamc1) MGI:8346383 (Muc1) MGI:8352275 (Myl2)
E Lats1/2^PanKO upper	MGI:8351675 (Lamc1) MGI:8346383 (Muc1) MGI:8352275 (Myl2)
E Lats1/2^PanKO lower	MGI:8351675 (Lamc1) MGI:8346383 (Muc1) MGI:8352275 (Myl2)