Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL2	HGNC:6001 (HGNC) 3558 (Entrez Gene) 147680 (OMIM) IL2 (Alliance of Genome Resources)	Chr4 q27	Chr4:122451470-122456725 (-) GRCh38	alopecia areata Alzheimer's disease asthma ataxia telangiectasia atopic dermatitis autoimmune thrombocytopenic purpura Behcet's disease bullous pemphigoid cholesteatoma of middle ear drug allergy graft-versus-host disease Graves' disease Graves ophthalmopathy head and neck squamous cell carcinoma hepatocellular carcinoma high grade glioma interstitial lung disease limited scleroderma oral squamous cell carcinoma pancreatic cancer pemphigus primary immunodeficiency disease renal cell carcinoma rheumatoid arthritis rhinitis sensorineural hearing loss squamous cell carcinoma systemic lupus erythematosus Takayasu's arteritis type 1 diabetes mellitus urinary bladder cancer viral hepatitis	P60568 (UniProt | EBI) NM_000586 (RefSeq)
mouse	Il2	MGI:96548 (MGI) 16183 (Entrez Gene) Gene Tree Il2 (Alliance of Genome Resources)	Chr3 18.3 cM	Chr3:37174862-37180103 (-) GRCm39	inflammatory bowel disease Sjogren's syndrome	16183 (NCBI Gene Model) P04351 (UniProt | EBI) NM_008366 (RefSeq)
rat	Il2	RGD:620047 (Rat Genome Database) 116562 (Entrez Gene) Il2 (Alliance of Genome Resources)	Chr2 q25			P17108 (UniProt | EBI) NM_053836 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.