Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT7B
  • Mouse genes Wnt7b
  • Rat genes Wnt7b
  • Zfish genes wnt7ba,wnt7bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1902379	chemoattractant activity involved in axon guidance	Wnt7b	IDA		Mouse	MGI:MGI:4866939|PMID:21106844
Molecular Function	GO:0005109	frizzled binding	Wnt7b	IPI	PR:Q61088	Mouse	PMID:16163358
Molecular Function	GO:0005109	frizzled binding	Wnt7b	IPI	PR:Q8BKG4	Mouse	PMID:15923619
Molecular Function	GO:0005109	frizzled binding	Wnt7b	IPI	PR:Q61088	Mouse	PMID:15923619
Molecular Function	GO:0005109	frizzled binding	Wnt7b	IPI	PR:O70421	Mouse	PMID:15923619
Molecular Function	GO:0005515	protein binding	WNT7B	IPI	UniProtKB:Q9Z0J1	Human	PMID:30026314
Molecular Function	GO:0005515	protein binding	Wnt7b	IPI	UniProtKB:Q9CWT0	Mouse	PMID:10866835
Molecular Function	GO:0048018	receptor ligand activity	WNT7B	IDA		Human	PMID:28733458
Cellular Component	GO:0009986	cell surface	Wnt7b	IDA		Mouse	MGI:MGI:66576|PMID:8167409
Cellular Component	GO:0005737	cytoplasm	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Cellular Component	GO:0005615	extracellular space	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Cellular Component	GO:0005886	plasma membrane	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0060033	anatomical structure regression	Wnt7b	IMP	MGI:MGI:3793960	Mouse	PMID:16163358
Biological Process	GO:0001525	angiogenesis	Wnt7b	IGI	MGI:MGI:98961	Mouse	PMID:19129494
Biological Process	GO:0001525	angiogenesis	Wnt7b	IMP	MGI:MGI:2387443	Mouse	PMID:19129494
Biological Process	GO:1902262	apoptotic process involved in blood vessel morphogenesis	Wnt7b	IMP	MGI:MGI:3793960	Mouse	PMID:16163358
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7B	IDA		Human	PMID:28733458
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IGI	MGI:MGI:108520	Mouse	PMID:16163358
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IGI	MGI:MGI:98961	Mouse	PMID:19023080
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IMP	MGI:MGI:3641208	Mouse	PMID:19690384
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IGI	MGI:MGI:1196625	Mouse	PMID:15923619
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IGI	MGI:MGI:1278315	Mouse	PMID:15923619
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IDA		Mouse	PMID:17804636
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IGI	MGI:MGI:2136761	Mouse	PMID:15923619
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0008283	cell population proliferation	Wnt7b	IMP	MGI:MGI:3641208	Mouse	PMID:19690384
Biological Process	GO:0021846	cell proliferation in forebrain	Wnt7b	IDA		Mouse	MGI:MGI:2667422|PMID:12843296
Biological Process	GO:0044237	cellular metabolic process	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0071300	cellular response to retinoic acid	WNT7B	IEP		Human	PMID:12239632
Biological Process	GO:0071300	cellular response to retinoic acid	WNT7B	IEP		Human	PMID:12429992
Biological Process	GO:0022009	central nervous system vasculogenesis	Wnt7b	IGI	MGI:MGI:98961	Mouse	PMID:19023080
Biological Process	GO:0036516	chemoattraction of dopaminergic neuron axon	Wnt7b	IDA		Mouse	MGI:MGI:4866939|PMID:21106844
Biological Process	GO:0060710	chorio-allantoic fusion	Wnt7b	IMP	MGI:MGI:2387443	Mouse	PMID:11543617
Biological Process	GO:0060560	developmental growth involved in morphogenesis	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0048568	embryonic organ development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0060669	embryonic placenta morphogenesis	Wnt7b	IMP	MGI:MGI:2387443	Mouse	PMID:11543617
Biological Process	GO:0016332	establishment or maintenance of polarity of embryonic epithelium	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0048144	fibroblast proliferation	WNT7B	IEP		Human	PMID:19734317
Biological Process	GO:0021871	forebrain regionalization	WNT7B	IEP		Human	PMID:15164427
Biological Process	GO:0021871	forebrain regionalization	Wnt7b	IEP		Mouse	MGI:MGI:4821941|PMID:15164427
Biological Process	GO:0042592	homeostatic process	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0001701	in utero embryonic development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0072061	inner medullary collecting duct development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0032364	intracellular oxygen homeostasis	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0060482	lobar bronchus development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0030324	lung development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18343501
Biological Process	GO:0060428	lung epithelium development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0060425	lung morphogenesis	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0060484	lung-associated mesenchyme development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0061180	mammary gland epithelium development	WNT7B	IEP		Human	PMID:8168088
Biological Process	GO:0072205	metanephric collecting duct development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0072207	metanephric epithelium development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0072236	metanephric loop of Henle development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0003338	metanephros morphogenesis	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0050768	negative regulation of neurogenesis	Wnt7b	IDA		Mouse	MGI:MGI:2667422|PMID:12843296
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Wnt7b	IMP		Mouse	PMID:10781055
Biological Process	GO:0030182	neuron differentiation	WNT7B	IEP		Human	PMID:12429992
Biological Process	GO:0031175	neuron projection development	Wnt7b	IMP		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0048812	neuron projection morphogenesis	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Wnt7b	IMP		Mouse	PMID:10781055
Biological Process	GO:0001649	osteoblast differentiation	Wnt7b	IDA		Mouse	PMID:15576404
Biological Process	GO:0072060	outer medullary collecting duct development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:1904938	planar cell polarity pathway involved in axon guidance	Wnt7b	IMP		Mouse	MGI:MGI:4866939|PMID:21106844
Biological Process	GO:0008284	positive regulation of cell population proliferation	Wnt7b	IMP	MGI:MGI:3641208	Mouse	PMID:19690384
Biological Process	GO:0010628	positive regulation of gene expression	Wnt7b	IMP	MGI:MGI:3641208	Mouse	PMID:19690384
Biological Process	GO:0046330	positive regulation of JNK cascade	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0046330	positive regulation of JNK cascade	Wnt7b	IMP		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Wnt7b	IDA		Mouse	PMID:15576404
Biological Process	GO:0032536	regulation of cell projection size	Wnt7b	IDA		Rat	PMID:18177422|RGD:2292645
Biological Process	GO:0072053	renal inner medulla development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0072054	renal outer medulla development	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:19060336
Biological Process	GO:0051384	response to glucocorticoid	Wnt7b	IEP		Rat	PMID:19099732|RGD:2326234
Biological Process	GO:0051145	smooth muscle cell differentiation	Wnt7b	IMP	MGI:MGI:3641208	Mouse	PMID:19690384
Biological Process	GO:0048864	stem cell development	Wnt7b	IDA		Mouse	MGI:MGI:2667422|PMID:12843296
Biological Process	GO:0072089	stem cell proliferation	WNT7B	IEP		Human	PMID:19734317
Biological Process	GO:0050808	synapse organization	Wnt7b	IGI	MGI:MGI:98961	Mouse	PMID:16818724
Biological Process	GO:0060535	trachea cartilage morphogenesis	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557
Biological Process	GO:0001944	vasculature development	Wnt7b	IMP	MGI:MGI:3793960	Mouse	PMID:16163358
Biological Process	GO:0016055	Wnt signaling pathway	Wnt7b	IMP	MGI:MGI:3793280	Mouse	PMID:18367557

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern