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Gene Ontology Browser
Term Detail
GO term:negative regulation of smoothened signaling pathway
Synonym: down regulation of smoothened signaling pathway
Synonym: down-regulation of smoothened signaling pathway
Synonym: downregulation of smoothened signaling pathway
Synonym: inhibition of smoothened signaling pathway
Synonym: negative regulation of hedgehog signaling pathway
Synonym: negative regulation of hh signaling pathway
Synonym: negative regulation of smoothened activity
Synonym: negative regulation of smoothened by patched
Synonym: negative regulation of smoothened receptor activity by patched
Synonym: negative regulation of smoothened signalling pathway
GO id:GO:0045879
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
Number of paths to term: 99

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of signaling
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of smoothened signaling pathway
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-apositive regulation of smoothened signaling pathway +
                                                                is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-asmoothened signaling pathway
                                                                part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                                is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                positively-regulatespositive regulation of smoothened signaling pathway +
                                                                regulatesregulation of smoothened signaling pathway +
                                                                part-ofsignal transduction downstream of smoothened +
                                                                is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                is-asmoothened signaling pathway involved in lung development
                                                                is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-asmoothened signaling pathway
                                                                regulatesregulation of smoothened signaling pathway
                                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                        is-apositive regulation of smoothened signaling pathway +
                                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                negatively-regulatesnegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of smoothened signaling pathway
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-apositive regulation of smoothened signaling pathway +
                                                                is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of signal transduction
                                                is-aregulation of smoothened signaling pathway
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-apositive regulation of smoothened signaling pathway +
                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-anegative regulation of signaling
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of signal transduction
                                                is-aregulation of smoothened signaling pathway
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-apositive regulation of smoothened signaling pathway +
                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        regulatesregulation of smoothened signaling pathway
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-apositive regulation of smoothened signaling pathway +
                                                                is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        negatively-regulatesnegative regulation of signal transduction
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of phosphorelay signal transduction system +
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of smoothened signaling pathway
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-apositive regulation of smoothened signaling pathway +
                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        negatively-regulatesnegative regulation of cellular process
                                is-anegative regulation of cell communication
                                        is-anegative regulation of signal transduction
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of phosphorelay signal transduction system +
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-aregulation of smoothened signaling pathway
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-apositive regulation of smoothened signaling pathway +
                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        regulatesregulation of smoothened signaling pathway
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-apositive regulation of smoothened signaling pathway +
                                                                is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        negatively-regulatesnegative regulation of signal transduction
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of phosphorelay signal transduction system +
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of smoothened signaling pathway
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-apositive regulation of smoothened signaling pathway +
                                                        is-aregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        negatively-regulatesnegative regulation of cell communication
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway [GO:0045879] (27 genes, 35 annotations)
                                                                        is-anegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        is-anegative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                            &