Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VSIR
  • Mouse genes Vsir
  • Rat genes Vsir
  • Zfish genes vsir
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vsir

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061133	endopeptidase activator activity	VSIR	IDA		Human	PMID:20666777
Molecular Function	GO:0019899	enzyme binding	VSIR	IPI	UniProtKB:P50281	Human	PMID:20666777
Molecular Function	GO:0042802	identical protein binding	VSIR	IPI	UniProtKB:Q9H7M9	Human	PMID:26228159
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:A0PK11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:O60636	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:P05090	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:P07306	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:P27449	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:P78383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q5BJF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q8IY26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q8N912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q8NBD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q8NHW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q8TBE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q969S0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q96GM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q9BXN2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q9NV29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q9P0S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIR	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Vsir	IPI	PR:P21275	Mouse	PMID:22751012
Molecular Function	GO:0005515	protein binding	Vsir	IPI	UniProtKB:P12644	Mouse	PMID:20042595
Cellular Component	GO:0009897	external side of plasma membrane	Vsir	IDA		Mouse	PMID:21768399
Cellular Component	GO:0009897	external side of plasma membrane	Vsir	IDA		Mouse	PMID:21383057
Cellular Component	GO:0009897	external side of plasma membrane	Vsir	IDA		Mouse	PMID:20042595
Cellular Component	GO:0005886	plasma membrane	VSIR	IDA		Human	PMID:20666777
Cellular Component	GO:0005886	plasma membrane	Vsir	IDA		Mouse	PMID:20042595
Biological Process	GO:0030509	BMP signaling pathway	Vsir	IGI	MGI:MGI:1338938	Mouse	PMID:20042595
Biological Process	GO:0030509	BMP signaling pathway	Vsir	IGI	MGI:MGI:2676809	Mouse	PMID:22751012
Biological Process	GO:0030509	BMP signaling pathway	Vsir	IMP		Mouse	PMID:20042595
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	VSIR	IMP		Human	PMID:24691993
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	Vsir	IDA		Mouse	PMID:21383057
Biological Process	GO:2000565	negative regulation of CD8-positive, alpha-beta T cell proliferation	VSIR	IMP		Human	PMID:24691993
Biological Process	GO:0032693	negative regulation of interleukin-10 production	VSIR	IDA		Human	PMID:24691993
Biological Process	GO:0032700	negative regulation of interleukin-17 production	VSIR	IDA		Human	PMID:24691993
Biological Process	GO:0002725	negative regulation of T cell cytokine production	Vsir	IDA		Mouse	PMID:21383057
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	VSIR	IDA		Human	PMID:24691993
Biological Process	GO:0032689	negative regulation of type II interferon production	VSIR	IDA		Human	PMID:24691993
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Vsir	IMP		Mouse	PMID:20042595
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Vsir	IGI	MGI:MGI:1338938	Mouse	PMID:20042595
Biological Process	GO:0030335	positive regulation of cell migration	VSIR	IDA		Human	PMID:20666777
Biological Process	GO:0120158	positive regulation of collagen catabolic process	VSIR	IDA		Human	PMID:20666777
Biological Process	GO:0010950	positive regulation of endopeptidase activity	VSIR	IDA		Human	PMID:20666777
Biological Process	GO:0010628	positive regulation of gene expression	VSIR	IMP		Human	PMID:20666777
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	VSIR	IMP		Human	PMID:24691993
Biological Process	GO:2000738	positive regulation of stem cell differentiation	Vsir	IGI	MGI:MGI:2676809	Mouse	PMID:22751012
Biological Process	GO:0048863	stem cell differentiation	Vsir	IGI	MGI:MGI:2676809	Mouse	PMID:22751012
Biological Process	GO:0048863	stem cell differentiation	Vsir	IMP		Mouse	PMID:20042595
Biological Process	GO:0031638	zymogen activation	VSIR	IDA		Human	PMID:20666777

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern