Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UROD
  • Mouse genes Urod
  • Rat genes Urod
  • Zfish genes urod
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Urod

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008198	ferrous iron binding	Urod	IDA		Rat	PMID:515872|RGD:4145087
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:Q96KN1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:Q96KN1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:C9JJ79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:P46019	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:Q96KN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UROD	IPI	UniProtKB:Q96PN8	Human	PMID:32296183
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:11069625
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:11719352
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:12071824
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:14633982
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:18004775
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	UROD	IDA		Human	PMID:21668429
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	Urod	IDA		Mouse	PMID:8661721
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	Urod	IMP	MGI:MGI:2687172	Mouse	PMID:11134514
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	Urod	IMP	MGI:MGI:2687172	Mouse	PMID:17360334
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	Urod	IDA		Rat	PMID:15736160|RGD:2301379
Molecular Function	GO:0004853	uroporphyrinogen decarboxylase activity	urod	IDA		Zfish	PMID:9806541
Cellular Component	GO:0005829	cytosol	UROD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Urod	IDA		Mouse	PMID:17360334
Cellular Component	GO:0005829	cytosol	Urod	IDA		Rat	PMID:12732362|RGD:2301380
Cellular Component	GO:0005654	nucleoplasm	UROD	IDA		Human	GO_REF:0000052
Biological Process	GO:0071243	cellular response to arsenic-containing substance	Urod	IEP		Rat	PMID:10416273|RGD:2303399
Biological Process	GO:0006783	heme biosynthetic process	Urod	IMP	MGI:MGI:2687172	Mouse	PMID:17360334
Biological Process	GO:0042168	heme metabolic process	Urod	IMP	MGI:MGI:2687172	Mouse	PMID:11134514
Biological Process	GO:0001889	liver development	Urod	IEP		Rat	PMID:6219675|RGD:4145103
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Urod	IDA		Rat	PMID:12381387|RGD:4144825
Biological Process	GO:0006787	porphyrin-containing compound catabolic process	UROD	IDA		Human	PMID:11069625
Biological Process	GO:0006787	porphyrin-containing compound catabolic process	UROD	IDA		Human	PMID:11719352
Biological Process	GO:0006787	porphyrin-containing compound catabolic process	UROD	IDA		Human	PMID:14633982
Biological Process	GO:0006787	porphyrin-containing compound catabolic process	UROD	IDA		Human	PMID:21668429
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	UROD	IDA		Human	PMID:12071824
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	urod	IDA		Zfish	PMID:9806541
Biological Process	GO:0014075	response to amine	Urod	IEP		Rat	PMID:10365252|RGD:4145076
Biological Process	GO:0032355	response to estradiol	Urod	IEP		Rat	PMID:3945969|RGD:4145104
Biological Process	GO:0045471	response to ethanol	Urod	IEP		Rat	PMID:12426626|RGD:4144182
Biological Process	GO:0060992	response to fungicide	Urod	IEP		Rat	PMID:19482825|RGD:4144824
Biological Process	GO:0010039	response to iron ion	Urod	IEP		Rat	PMID:891100|RGD:4145101
Biological Process	GO:0046689	response to mercury ion	Urod	IEP		Rat	PMID:6482878|RGD:4145085
Biological Process	GO:0051597	response to methylmercury	Urod	IEP		Rat	PMID:3327437|RGD:4145123
Biological Process	GO:0014070	response to organic cyclic compound	Urod	IEP		Rat	PMID:4023421|RGD:4145083
Biological Process	GO:0046502	uroporphyrinogen III metabolic process	Urod	IDA		Rat	PMID:15736160|RGD:2301379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern