Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSKU
  • Mouse genes Tsku
  • Rat genes Tsku
  • Zfish genes tsku
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tsku

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Tsku	IPI	UniProtKB:P29279	Mouse	MGI:MGI:6478064|PMID:30232710
Molecular Function	GO:0005515	protein binding	Tsku	IPI	PR:Q61088	Mouse	PMID:21856951
Molecular Function	GO:0050431	transforming growth factor beta binding	Tsku	IPI	UniProtKB:P04202	Mouse	MGI:MGI:5449316|PMID:22995554
Cellular Component	GO:0005615	extracellular space	Tsku	IDA		Mouse	MGI:MGI:6407480|PMID:31391339
Cellular Component	GO:0005615	extracellular space	Tsku	IDA		Mouse	MGI:MGI:6392476|PMID:31535079
Cellular Component	GO:0005615	extracellular space	Tsku	IDA		Mouse	PMID:21856951
Biological Process	GO:0021960	anterior commissure morphogenesis	Tsku	IMP		Mouse	MGI:MGI:5467661|PMID:23206892
Biological Process	GO:0021960	anterior commissure morphogenesis	Tsku	IMP	MGI:MGI:4867728	Mouse	PMID:21055390
Biological Process	GO:0043010	camera-type eye development	Tsku	IMP		Mouse	PMID:21856951
Biological Process	GO:0033344	cholesterol efflux	Tsku	IMP		Mouse	MGI:MGI:6407480|PMID:31391339
Biological Process	GO:0042632	cholesterol homeostasis	Tsku	IMP		Mouse	MGI:MGI:6407480|PMID:31391339
Biological Process	GO:0008203	cholesterol metabolic process	Tsku	IMP		Mouse	MGI:MGI:6407480|PMID:31391339
Biological Process	GO:0061073	ciliary body morphogenesis	Tsku	IMP		Mouse	PMID:21856951
Biological Process	GO:0021540	corpus callosum morphogenesis	Tsku	IMP	MGI:MGI:4867728	Mouse	PMID:21055390
Biological Process	GO:0097009	energy homeostasis	Tsku	IMP		Mouse	MGI:MGI:6392476|PMID:31535079
Biological Process	GO:0021766	hippocampus development	Tsku	IMP		Mouse	MGI:MGI:6478862|PMID:31983064
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Tsku	IMP		Mouse	MGI:MGI:6416702|PMID:32127020
Biological Process	GO:0021670	lateral ventricle development	Tsku	IMP	MGI:MGI:4867728	Mouse	PMID:21055390
Biological Process	GO:1904761	negative regulation of myofibroblast differentiation	Tsku	IMP		Mouse	MGI:MGI:6478057|PMID:25159578
Biological Process	GO:0010977	negative regulation of neuron projection development	Tsku	IMP		Mouse	MGI:MGI:5467661|PMID:23206892
Biological Process	GO:0032911	negative regulation of transforming growth factor beta1 production	Tsku	IMP		Mouse	MGI:MGI:6478057|PMID:25159578
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	Tsku	IDA		Mouse	PMID:21856951
Biological Process	GO:0042635	positive regulation of hair cycle	Tsku	IMP		Mouse	MGI:MGI:5449316|PMID:22995554
Biological Process	GO:0010468	regulation of gene expression	Tsku	IMP		Mouse	PMID:21856951
Biological Process	GO:0042060	wound healing	Tsku	IMP		Mouse	MGI:MGI:6478057|PMID:25159578

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern