Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TEF
  • Mouse genes Tef
  • Rat genes Tef
  • Zfish genes tefa,tefb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tef

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tef	IDA		Rat	PMID:1916262|RGD:70036
Molecular Function	GO:0003690	double-stranded DNA binding	Tef	IDA		Mouse	PMID:1916262
Molecular Function	GO:0042802	identical protein binding	Tef	IPI	RGD:3841	Rat	PMID:1916262|RGD:70036
Molecular Function	GO:0005515	protein binding	TEF	IPI	UniProtKB:Q13084	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TEF	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TEF	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Tef	IPI	PR:Q9JLC6	Mouse	PMID:1916262
Molecular Function	GO:0044877	protein-containing complex binding	Tef	IDA		Rat	PMID:1916262|RGD:70036
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tef	IDA		Rat	PMID:1916262|RGD:70036
Molecular Function	GO:0043565	sequence-specific DNA binding	Tef	IDA		Rat	PMID:1916262|RGD:70036
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TEF	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Tef	IDA		Rat	PMID:1916262|RGD:70036
Biological Process	GO:0071482	cellular response to light stimulus	tefb	IMP	ZFIN:ZDB-MRPHLNO-110411-1	Zfish	PMID:21390203
Biological Process	GO:0071482	cellular response to light stimulus	tefa	IMP	ZFIN:ZDB-MRPHLNO-101015-4,ZFIN:ZDB-MRPHLNO-101015-5	Zfish	PMID:20830285
Biological Process	GO:0071482	cellular response to light stimulus	tefa	IMP	ZFIN:ZDB-MRPHLNO-100514-3	Zfish	PMID:21390203
Biological Process	GO:0071482	cellular response to light stimulus	tefa	IMP	ZFIN:ZDB-MRPHLNO-101015-4	Zfish	PMID:20830285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	tefa	IMP	ZFIN:ZDB-MRPHLNO-101015-4,ZFIN:ZDB-MRPHLNO-101015-5	Zfish	PMID:20830285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	tefa	IMP	ZFIN:ZDB-MRPHLNO-101015-5	Zfish	PMID:20830285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	tefa	IMP	ZFIN:ZDB-MRPHLNO-101015-4	Zfish	PMID:20830285
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tef	IDA		Mouse	PMID:1916262
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tef	IDA		Rat	PMID:1916262|RGD:70036

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern