Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tcf12

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TCF12
- Mouse genes Tcf12
- Rat genes Tcf12
- Zfish genes tcf12
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcf12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	TCF12	IPI	UniProtKB:P15923	Human	PMID:21828274
Molecular Function	GO:0035497	cAMP response element binding	Tcf12	IDA		Rat	PMID:7683670\|RGD:729997
Molecular Function	GO:0003677	DNA binding	Tcf12	IDA		Mouse	PMID:1922066
Molecular Function	GO:0003677	DNA binding	Tcf12	IDA		Mouse	PMID:1321336
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	TCF12	IDA		Human	PMID:11802795
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TCF12	IDA		Human	PMID:11802795
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TCF12	IPI	UniProtKB:O75593	Human	PMID:21828274
Molecular Function	GO:0070888	E-box binding	Tcf12	IDA		Mouse	MGI:MGI:3789797\|PMID:18214987
Molecular Function	GO:0071837	HMG box domain binding	Tcf12	IPI	UniProtKB:O55170	Rat	PMID:16582099\|RGD:6892704
Molecular Function	GO:0071837	HMG box domain binding	Tcf12	IPI	UniProtKB:Q04886	Rat	PMID:16582099\|RGD:6892704
Molecular Function	GO:0071837	HMG box domain binding	Tcf12	IPI	UniProtKB:Q05066	Rat	PMID:16582099\|RGD:6892704
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:O96004	Human	PMID:11802795
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q02363	Human	PMID:16549780
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q02363	Human	PMID:19321746
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P17542	Human	PMID:19497860
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P41134	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q02535	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P17542	Human	PMID:21179004
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q96MH2	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:O75593	Human	PMID:21828274
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:O60336	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:O75575	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:O75716	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P25786	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P30626	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P42229	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P42773	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P47897	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P47897-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q02535	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q1RLL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q3B7T1-5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q548N1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q6P2C6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q6XD76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q6ZMU5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q8IUR7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q8IYR0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q8NDC4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q8WVJ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q8WVZ3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q96MC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q96MH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q96S90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q99598	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9BPY8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9NX04	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9NZD8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9UJ70	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9UJX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9Y4Z2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q7RTU4	Human	PMID:25466284
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P41134	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q96C12	Human	PMID:28169274
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P25786	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P42773	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P47897	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q02535	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9NZD8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9UJX0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:Q9Y4Z2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P17542	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	TCF12	IPI	UniProtKB:P17542	Human	PMID:9824680
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	UniProtKB:P15923-2	Mouse	MGI:MGI:3706493\|PMID:10958665
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	UniProtKB:P22091	Mouse	MGI:MGI:5508258\|PMID:16407974
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	PR:Q62414	Mouse	PMID:18214987
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	PR:P20067	Mouse	PMID:1922066
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	PR:P41136	Mouse	PMID:1922066
Molecular Function	GO:0005515	protein binding	Tcf12	IPI	PR:Q61039	Mouse	PMID:15351717
Molecular Function	GO:0046982	protein heterodimerization activity	Tcf12	IDA		Mouse	MGI:MGI:3789797\|PMID:18214987
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	TCF12	IDA		Human	PMID:11802795
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TCF12	IDA		Human	PMID:28473536
Molecular Function	GO:0046332	SMAD binding	TCF12	IPI	UniProtKB:P84022	Human	PMID:21828274
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TCF12	IDA		Human	PMID:11802795
Cellular Component	GO:0000785	chromatin	TCF12	IDA		Human	PMID:21828274
Cellular Component	GO:0005737	cytoplasm	TCF12	IDA		Human	PMID:21828274
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TCF12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	TCF12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TCF12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TCF12	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	TCF12	IDA		Human	PMID:21828274
Cellular Component	GO:0005634	nucleus	Tcf12	IDA		Rat	PMID:9418957\|RGD:8554264
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	TCF12	IDA		Human	PMID:11802795
Cellular Component	GO:0005667	transcription regulator complex	Tcf12	IDA		Mouse	PMID:15351717
Biological Process	GO:0010467	gene expression	Tcf12	IMP	MGI:MGI:2387400	Mouse	PMID:18958875
Biological Process	GO:0010467	gene expression	Tcf12	IMP	MGI:MGI:3707160	Mouse	PMID:18958875
Biological Process	GO:0031175	neuron projection development	tcf12	IMP	ZFIN:ZDB-MRPHLNO-210317-3	Zfish	PMID:32620954
Biological Process	GO:0031175	neuron projection development	tcf12	IMP	ZFIN:ZDB-MRPHLNO-210317-4	Zfish	PMID:32620954
Biological Process	GO:0031175	neuron projection development	tcf12	IMP	ZFIN:ZDB-CRISPR-210317-3	Zfish	PMID:32620954
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tcf12	IDA		Mouse	PMID:1321336
Biological Process	GO:0010628	positive regulation of gene expression	Tcf12	IMP	MGI:MGI:2387400	Mouse	PMID:18958875
Biological Process	GO:0010628	positive regulation of gene expression	Tcf12	IMP	MGI:MGI:3707160	Mouse	PMID:18958875
Biological Process	GO:0045666	positive regulation of neuron differentiation	Tcf12	IDA		Mouse	MGI:MGI:3789797\|PMID:18214987
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TCF12	IDA		Human	PMID:11802795
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tcf12	IDA		Rat	PMID:7683670\|RGD:729997
Biological Process	GO:0097210	response to gonadotropin-releasing hormone	TCF12	IMP		Human	PMID:32620954

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.