Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBL1X,TBL1Y
  • Mouse genes Tbl1x
  • Rat genes Tbl1x
  • Zfish genes tbl1x
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbl1x

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Tbl1x	IDA		Mouse	PMID:15728386
Molecular Function	GO:0003677	DNA binding	Tbl1x	IDA		Mouse	PMID:14980219
Molecular Function	GO:0042393	histone binding	TBL1X	IDA		Human	PMID:15601853
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:Q9Y618	Human	PMID:10809664
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:Q13227	Human	PMID:11931768
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:O75376	Human	PMID:12628926
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:P35222	Human	PMID:18193033
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:Q9NQB0	Human	PMID:18193033
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:Q13363	Human	PMID:18374649
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TBL1X	IPI	UniProtKB:P36405	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBL1Y	IPI	UniProtKB:Q9Y618	Human	PMID:30341416
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	UniProtKB:Q9Z2D6	Mouse	MGI:MGI:5904547|PMID:28348241
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	UniProtKB:Q13227	Mouse	MGI:MGI:5688415|PMID:26070566
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	UniProtKB:P51608	Mouse	MGI:MGI:5528617|PMID:23770565
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	PR:P61080	Mouse	PMID:14980219
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	PR:P45481	Mouse	PMID:14980219
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	PR:Q8CBD1	Mouse	PMID:14980219
Molecular Function	GO:0005515	protein binding	Tbl1x	IPI	PR:O08686	Mouse	PMID:15728386
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TBL1X	IDA		Human	PMID:18193033
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Tbl1x	IDA		Mouse	MGI:MGI:3604169|PMID:16127449
Molecular Function	GO:0003714	transcription corepressor activity	TBL1X	IDA		Human	PMID:12628926
Molecular Function	GO:0003714	transcription corepressor activity	TBL1X	IGI	UniProtKB:Q9BZK7	Human	PMID:15601853
Molecular Function	GO:0003714	transcription corepressor activity	Tbl1x	IMP		Mouse	PMID:14980219
Cellular Component	GO:0000118	histone deacetylase complex	TBL1X	IDA		Human	PMID:18326024
Cellular Component	GO:0072686	mitotic spindle	TBL1X	IDA		Human	PMID:18326024
Cellular Component	GO:0005654	nucleoplasm	TBL1Y	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TBL1X	IDA		Human	PMID:18193033
Cellular Component	GO:0005634	nucleus	TBL1Y	IDA		Human	PMID:30341416
Cellular Component	GO:0005667	transcription regulator complex	Tbl1x	IDA		Mouse	PMID:15728386
Cellular Component	GO:0017053	transcription repressor complex	TBL1X	IDA		Human	PMID:12628926
Cellular Component	GO:0017053	transcription repressor complex	TBL1X	IDA		Human	PMID:15601853
Biological Process	GO:0045444	fat cell differentiation	Tbl1x	IMP		Mouse	PMID:14980219
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Tbl1x	IMP		Mouse	PMID:14980219
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TBL1X	IDA		Human	PMID:12628926
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	TBL1X	IMP		Human	PMID:18193033
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TBL1X	IDA		Human	PMID:18193033
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TBL1X	IDA		Human	PMID:18193033
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tbl1x	IMP		Mouse	MGI:MGI:3604169|PMID:16127449
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Tbl1x	IMP		Mouse	PMID:14980219
Biological Process	GO:0050821	protein stabilization	Tbl1x	IDA		Mouse	MGI:MGI:5688415|PMID:26070566
Biological Process	GO:0006508	proteolysis	TBL1X	IMP		Human	PMID:18374649
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Tbl1x	IGI	MGI:MGI:109617	Mouse	PMID:15728386
Biological Process	GO:0043627	response to estrogen	Tbl1x	IMP		Mouse	PMID:14980219
Biological Process	GO:0048545	response to steroid hormone	Tbl1x	IMP		Mouse	PMID:14980219
Biological Process	GO:0007605	sensory perception of sound	TBL1X	IMP		Human	PMID:10330347

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern