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Tbl1x Gene Detail
Summary
  • Symbol
    Tbl1x
  • Name
    transducin (beta)-like 1 X-linked
  • Synonyms
    Tbl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336172
    NCBI Gene: 21372
  • Gene Overview
    MyGene.info: TBL1X
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    ChrX:77511013-77662983 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      151971 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.31 cM, cytoband B-C
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    TBL1X, transducin beta like 1 X-linked
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TBL1X, transducin beta like 1 X-linked
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EBI, SMAP55, TBL1
  • Links
    NCBI Gene ID: 6907
    neXtProt AC: NX_O60907
    UniProt: O60907

  • Chr Location
    Xp22.31-p22.2; chrX:9463295-9719740 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    15
  • Tissues
    15
  • cDNA Data
    13
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017892 VEGA Gene Model | MGI Sequence Detail 151971 C57BL/6J ±  kb
transcript OTTMUST00000043270 VEGA | MGI Sequence Detail 5234 Not Applicable  
polypeptide OTTMUSP00000019452 VEGA | MGI Sequence Detail 527 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    396 from dbSNP Build 142
  • RFLP
    1
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 13
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:52006 Disteche CM, et al., Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes. Mamm Genome. 1998 Dec;9(12):1062-4
  • Latest
    J:242147 Kruusvee V, et al., Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3243-E3250
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/17/2018
MGI 6.11 		The Jackson Laboratory