Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYT6
  • Mouse genes Syt6
  • Rat genes Syt6
  • Zfish genes syt6a,syt6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syt6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt6	IDA		Mouse	MGI:MGI:5795832|PMID:8626542
Molecular Function	GO:0048306	calcium-dependent protein binding	Syt6	IPI	UniProtKB:O35526|UniProtKB:P61264	Mouse	MGI:MGI:3584221|PMID:15774481
Molecular Function	GO:0048306	calcium-dependent protein binding	Syt6	IPI	UniProtKB:Q00262	Mouse	MGI:MGI:3584221|PMID:15774481
Molecular Function	GO:0030276	clathrin binding	SYT6	IDA		Human	PMID:7791877
Molecular Function	GO:0042802	identical protein binding	Syt6	IPI	UniProtKB:Q9R0N8	Mouse	MGI:MGI:1858287|PMID:10531343
Molecular Function	GO:0001786	phosphatidylserine binding	Syt6	IDA		Mouse	MGI:MGI:5780544|PMID:12860971
Molecular Function	GO:0005515	protein binding	Syt6	IPI	UniProtKB:O35681|UniProtKB:Q9R0N4|UniProtKB:Q9R0N9	Mouse	MGI:MGI:1858287|PMID:10531343
Molecular Function	GO:0005515	protein binding	Syt6	IPI	UniProtKB:O35681	Mouse	MGI:MGI:5285165|PMID:20002670
Molecular Function	GO:0046982	protein heterodimerization activity	Syt6	IPI	UniProtKB:Q9R0N4|UniProtKB:Q9R0N5	Mouse	MGI:MGI:5142391|PMID:10531344
Molecular Function	GO:0042803	protein homodimerization activity	Syt6	IPI	UniProtKB:Q9R0N8-1	Mouse	MGI:MGI:5142391|PMID:10531344
Molecular Function	GO:0042803	protein homodimerization activity	Syt6	IDA		Mouse	MGI:MGI:1858287|PMID:10531343
Molecular Function	GO:0019905	syntaxin binding	SYT6	IDA		Human	PMID:7791877
Molecular Function	GO:0019905	syntaxin binding	Syt6	IDA		Rat	PMID:7791877|RGD:61762
Cellular Component	GO:0005829	cytosol	Syt6	IDA		Mouse	MGI:MGI:5142391|PMID:10531344
Cellular Component	GO:0019898	extrinsic component of membrane	Syt6	IDA		Mouse	MGI:MGI:5142391|PMID:10531344
Cellular Component	GO:0098978	glutamatergic synapse	Syt6	IDA		Rat	PMID:26216953|RGD:13702162
Cellular Component	GO:0098978	glutamatergic synapse	Syt6	IMP		Rat	PMID:26216953|RGD:13702162
Cellular Component	GO:0016020	membrane	Syt6	IDA		Mouse	MGI:MGI:5142391|PMID:10531344
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	Syt6	IDA		Mouse	MGI:MGI:5142391|PMID:10531344
Cellular Component	GO:0005886	plasma membrane	Syt6	IDA		Mouse	MGI:MGI:5142391|PMID:10531344
Cellular Component	GO:0097060	synaptic membrane	Syt6	EXP		Rat	PMID:10373432|RGD:13702215
Cellular Component	GO:0097060	synaptic membrane	Syt6	IDA		Rat	PMID:10373432|RGD:13702215
Biological Process	GO:0060478	acrosomal vesicle exocytosis	SYT6	IMP		Human	PMID:11437455
Biological Process	GO:0007340	acrosome reaction	Syt6	IDA		Mouse	MGI:MGI:3584221|PMID:15774481
Biological Process	GO:0150038	postsynaptic dense core vesicle exocytosis	Syt6	IDA		Rat	PMID:26216953|RGD:13702162
Biological Process	GO:0150038	postsynaptic dense core vesicle exocytosis	Syt6	IMP		Rat	PMID:26216953|RGD:13702162

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern