About   Help   FAQ
Syt6
Gene Detail
Symbol

Name
ID
Syt6
synaptotagmin VI
MGI:1859544
Synonyms
3110037A08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.45 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:103575231-103645569 bp, + strand
From VEGA annotation of GRCm38

  70339 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10301  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SYT6
Protein SuperFamily: B/K protein/synaptotagmin
Gene Tree: Syt6

Human
homologs
SYT6, synaptotagmin VI
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 148281
neXtProt AC: NX_Q5T7P8

Human Synonyms: sytVI

Human Chr (Location): 1p13.2; chr1:114089292-114153850 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Syt6 interacts with 429 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process acrosomal vesicle exocytosis, acrosome reaction, ...
Component cell, cell junction, ...
Function calcium-dependent phospholipid binding, calcium-dependent protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (176)    Tissues (95)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 176
cDNA source data(7)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase syt6    NEW 
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000028617 (Evidence)
Ensembl Gene Model ENSMUSG00000027849 (Evidence)
Entrez Gene 54524 (Evidence)
DFCI TC1595832, TC1588081, TC1760026, TC1601560
DoTS DT.91336611, DT.87048610, DT.94221885, DT.97382307, DT.60102509, DT.103548124, DT.101179515
NIA Mouse Gene Index U003668
Consensus CDS Project CCDS38575.1, CCDS71296.1, CCDS71297.1
International Mouse Phenotyping Consortium Status Syt6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028617 VEGA Gene Model | MGI Sequence Detail 70339 C57BL/6J ±  kb
transcript OTTMUST00000070915 VEGA | MGI Sequence Detail 1710 Not Applicable 
polypeptide OTTMUSP00000036211 VEGA | MGI Sequence Detail 511 Not Applicable 

For the selected sequences
All sequences(94) RefSeq(25) UniProt(8)
Polymorphisms
SNPs within 2kb(542 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR001565 Synaptotagmin
Protein Ontology PR:000015908 synaptotagmin-6
References
(Earliest) J:62060 Fukuda M, et al., Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. J Biol Chem. 1999 Oct 29;274(44):31421-7
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(41)
Other
accession IDs
MGI:1925594, MGI:2139957

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory