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Syt6
Gene Detail
Symbol

Name
ID
Syt6
synaptotagmin VI
MGI:1859544
Synonyms
3110037A08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.45 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:103575231-103645569 bp, + strand
From VEGA annotation of GRCm38

  70339 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10301  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: B/K protein/synaptotagmin
Gene Tree: Syt6

Human
homologs
Human Homolog SYT6, synaptotagmin VI
NCBI Gene ID 148281
neXtProt AC  NX_Q5T7P8
Human Synonyms  sytVI
Human Chr (Location)  1p13.2; chr1:114089292-114153850 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Syt6 interacts with 430 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process acrosomal vesicle exocytosis, acrosome reaction, ...
Component cell, cell junction, ...
Function calcium-dependent protein binding, clathrin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (176)    Tissues (95)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 176
cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000028617 (Evidence)
Ensembl Gene ModelENSMUSG00000027849 (Evidence)
Entrez Gene54524 (Evidence)
DFCITC1588081, TC1595832, TC1601560, TC1760026
DoTSDT.101179515, DT.103548124, DT.60102509, DT.87048610, DT.91336611, DT.94221885, DT.97382307
NIA Mouse Gene IndexU003668
Consensus CDS ProjectCCDS38575.1, CCDS71296.1, CCDS71297.1
International Mouse Knockout Project StatusSyt6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028617 VEGA Gene Model | MGI Sequence Detail 70339 C57BL/6J ±  kb
transcript OTTMUST00000070915 VEGA | MGI Sequence Detail 1710 Not Applicable 
polypeptide OTTMUSP00000036211 VEGA | MGI Sequence Detail 511 Not Applicable 

For the selected sequences
All sequences(101) RefSeq(25) UniProt(15)
Polymorphisms
SNPs within 2kb(542 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR001565 Synaptotagmin
Protein Ontology PR:000015908 synaptotagmin-6
References
(Earliest) J:62060 Fukuda M, et al., Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. J Biol Chem. 1999 Oct 29;274(44):31421-7
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(42)
Other
accession IDs
MGI:1925594, MGI:2139957

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory