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Syt6 Gene Detail
Summary
  • Symbol
    Syt6
  • Name
    synaptotagmin VI
  • Synonyms
    3110037A08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859544
    NCBI Gene: 54524
  • Gene Overview
    MyGene.info: SYT6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:103575242-103645567 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.45 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    538 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859544
protein coding gene Chr3:103575231-103645569 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027694
protein coding gene Chr3:104864085-104921511 (+)
A/J MGP_AJ_G0027653
protein coding gene Chr3:101521651-101591655 (+)
AKR/J MGP_AKRJ_G0027619
protein coding gene Chr3:104004267-104064307 (+)
BALB/cJ MGP_BALBcJ_G0027666
protein coding gene Chr3:101286183-101362359 (+)
C3H/HeJ MGP_C3HHeJ_G0027395
protein coding gene Chr3:104357798-104438827 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028109
protein coding gene Chr3:108750574-108831204 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025450
protein coding gene Chr3:97652583-97712691 (+)
CAST/EiJ MGP_CASTEiJ_G0026852
protein coding gene Chr3:103471011-103541631 (+)
CBA/J MGP_CBAJ_G0027370
protein coding gene Chr3:112487882-112560961 (+)
DBA/2J MGP_DBA2J_G0027513
protein coding gene Chr3:100764188-100835791 (+)
FVB/NJ MGP_FVBNJ_G0027481
protein coding gene Chr3:98693233-98751828 (+)
LP/J MGP_LPJ_G0027620
protein coding gene Chr3:106201585-106259407 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027510
protein coding gene Chr3:118599420-118672594 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028164
protein coding gene Chr3:103549539-103624693 (+)
PWK/PhJ MGP_PWKPhJ_G0026578
protein coding gene Chr3:100535374-100596612 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026400
protein coding gene Chr3:101630398-101690493 (+)
WSB/EiJ MGP_WSBEiJ_G0026931
protein coding gene Chr3:104100676-104161803 (+)



Homology
more
  • Human Ortholog
    SYT6, synaptotagmin 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYT6, synaptotagmin 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    sytVI
  • Links
    NCBI Gene ID: 148281
    neXtProt AC: NX_Q5T7P8
    UniProt: Q5T7P8

  • Chr Location
    1p13.2; chr1:114089292-114153919 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54524 NCBI Gene Model | MGI Sequence Detail 70326 C57BL/6J ±  kb
transcript NM_018800 RefSeq | MGI Sequence Detail 4473 C57BL/6  
polypeptide Q9R0N8 UniProt | EBI | MGI Sequence Detail 511 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1925594, MGI:2139957
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Diseases 1
    Gene Ontology 12
    Phenotypes 6
  • Earliest
    J:235272 Fukuda M, et al., Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV. J Biol Chem. 1996 Apr 5;271(14):8430-4
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory