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Term Detail
GO term:extrinsic component of membrane
Synonym: extrinsic to membrane
Synonym: peripheral membrane protein
GO id:GO:0019898
Alternate id: GO:0030396
Definition:The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
CommentsNote that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aendoplasmic reticulum membrane +
                                is-aextrinsic component of membrane [GO:0019898] (255 genes, 314 annotations)
                                        is-aextrinsic component of cell outer membrane +
                                        is-aextrinsic component of organelle membrane +
                                        is-aextrinsic component of plasma membrane +
                                        is-aextrinsic component of thylakoid membrane +
                                        part-ofphosphatidylinositol 3-kinase complex +
                                is-aintrinsic component of membrane +
                                is-aleaflet of membrane bilayer
                                is-amembrane protein complex +
                                is-amembrane region +
                                is-amitochondrial membrane part +
                                is-anuclear membrane part +
                                is-anuclear outer membrane +
                                is-aplasma membrane part +
                                is-arespiratory chain +
                                is-aside of membrane +


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aendoplasmic reticulum membrane +
                        is-aextrinsic component of membrane [GO:0019898] (255 genes, 314 annotations)
                                is-aextrinsic component of cell outer membrane +
                                is-aextrinsic component of organelle membrane +
                                is-aextrinsic component of plasma membrane +
                                is-aextrinsic component of thylakoid membrane +
                                part-ofphosphatidylinositol 3-kinase complex +
                        is-aintrinsic component of membrane +
                        is-aleaflet of membrane bilayer
                        is-amembrane protein complex +
                        is-amembrane region +
                        is-amitochondrial membrane part +
                        is-anuclear membrane part +
                        is-anuclear outer membrane +
                        is-aplasma membrane part +
                        is-arespiratory chain +
                        is-aside of membrane +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory