Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SULF1
  • Mouse genes Sulf1
  • Rat genes Sulf1
  • Zfish genes sulf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sulf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004065	arylsulfatase activity	SULF1	IDA		Human	PMID:12368295
Molecular Function	GO:0004065	arylsulfatase activity	SULF1	IMP		Human	PMID:19520866
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF1	IDA		Human	PMID:12686563
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF1	IDA		Human	PMID:18687675
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF1	IMP		Human	PMID:19520866
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF1	IDA		Human	PMID:19666466
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	Sulf1	IMP		Mouse	MGI:MGI:5306289|PMID:18687675
Cellular Component	GO:0009986	cell surface	SULF1	IDA		Human	PMID:12368295
Cellular Component	GO:0009986	cell surface	SULF1	IDA		Human	PMID:12686563
Cellular Component	GO:0009986	cell surface	SULF1	IDA		Human	PMID:18687675
Cellular Component	GO:0009986	cell surface	SULF1	IDA		Human	PMID:19520866
Cellular Component	GO:0009986	cell surface	SULF1	IDA		Human	PMID:19666466
Cellular Component	GO:0009986	cell surface	Sulf1	IDA		Rat	PMID:11895481|RGD:1302407
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SULF1	HDA		Human	PMID:28327460
Cellular Component	GO:0005783	endoplasmic reticulum	SULF1	IDA		Human	PMID:18687675
Cellular Component	GO:0005783	endoplasmic reticulum	Sulf1	IDA		Rat	PMID:11895481|RGD:1302407
Cellular Component	GO:0005615	extracellular space	SULF1	IDA		Human	PMID:19666466
Cellular Component	GO:0005615	extracellular space	SULF1	HDA		Human	PMID:22664934
Cellular Component	GO:0005794	Golgi apparatus	Sulf1	IDA		Rat	PMID:11895481|RGD:1302407
Cellular Component	GO:0045121	membrane raft	SULF1	IDA		Human	PMID:19520866
Cellular Component	GO:0005886	plasma membrane	Sulf1	IDA		Mouse	MGI:MGI:5306737|PMID:21719793
Biological Process	GO:0008015	blood circulation	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-2	Zfish	PMID:23959107
Biological Process	GO:0008015	blood circulation	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-1	Zfish	PMID:23959107
Biological Process	GO:0060348	bone development	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3769052|PMID:17593974
Biological Process	GO:0051216	cartilage development	Sulf1	IMP		Mouse	MGI:MGI:5306560|PMID:20479257
Biological Process	GO:0002063	chondrocyte development	Sulf1	IMP		Mouse	MGI:MGI:5306560|PMID:20479257
Biological Process	GO:0048706	embryonic skeletal system development	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3771123|PMID:18213582
Biological Process	GO:0010669	epithelial structure maintenance	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-2	Zfish	PMID:31428635
Biological Process	GO:0010669	epithelial structure maintenance	sulf1	IGI	ZFIN:ZDB-GENE-040426-759,ZFIN:ZDB-GENE-030131-775	Zfish	PMID:31428635
Biological Process	GO:0014846	esophagus smooth muscle contraction	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3722747|PMID:17720696
Biological Process	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	Sulf1	IDA		Mouse	MGI:MGI:3722747|PMID:17720696
Biological Process	GO:0032836	glomerular basement membrane development	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:5306737|PMID:21719793
Biological Process	GO:0003094	glomerular filtration	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:5306737|PMID:21719793
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	SULF1	IDA		Human	PMID:18687675
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	SULF1	IDA		Human	PMID:19666466
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	SULF1	IDA		Human	PMID:19822709
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	Sulf1	IMP		Mouse	MGI:MGI:5306289|PMID:18687675
Biological Process	GO:0060384	innervation	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3722747|PMID:17720696
Biological Process	GO:0001822	kidney development	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3769052|PMID:17593974
Biological Process	GO:0016525	negative regulation of angiogenesis	SULF1	IDA		Human	PMID:16778174
Biological Process	GO:0030336	negative regulation of cell migration	SULF1	IMP		Human	PMID:21266348
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	SULF1	IDA		Human	PMID:16778174
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	SULF1	IMP		Human	PMID:20479257
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Sulf1	IDA		Mouse	MGI:MGI:4941125|PMID:20410206
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:5306737|PMID:21719793
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3769052|PMID:17593974
Biological Process	GO:0060686	negative regulation of prostatic bud formation	Sulf1	IDA		Mouse	MGI:MGI:4941125|PMID:20410206
Biological Process	GO:0048885	neuromast deposition	sulf1	IMP	ZFIN:ZDB-MRPHLNO-130805-3	Zfish	PMID:23583585
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	SULF1	IMP		Human	PMID:20479257
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	Sulf1	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:5306737|PMID:21719793
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	SULF1	IDA		Human	PMID:19520866
Biological Process	GO:0048070	regulation of developmental pigmentation	sulf1	IMP	ZFIN:ZDB-MRPHLNO-130805-3	Zfish	PMID:23583585
Biological Process	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	SULF1	IMP		Human	PMID:21266348
Biological Process	GO:2000290	regulation of myotome development	sulf1	IMP	ZFIN:ZDB-MRPHLNO-130805-3	Zfish	PMID:23583585
Biological Process	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140609-1	Zfish	PMID:24595292
Biological Process	GO:0001756	somitogenesis	sulf1	IMP	ZFIN:ZDB-MRPHLNO-130805-3	Zfish	PMID:23583585
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	SULF1	IDA		Human	PMID:16778174
Biological Process	GO:0001944	vasculature development	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-1	Zfish	PMID:23959107
Biological Process	GO:0001570	vasculogenesis	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-1	Zfish	PMID:23959107
Biological Process	GO:0001570	vasculogenesis	sulf1	IMP	ZFIN:ZDB-MRPHLNO-140321-2	Zfish	PMID:23959107

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern