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Gene Ontology Browser
Term Detail
GO term:cartilage development
Synonym: cartilage biogenesis
Synonym: cartilage biosynthesis
Synonym: cartilage element development
Synonym: cartilage formation
Synonym: cartilage organ development
Synonym: chondrogenesis
GO id:GO:0051216
Definition:The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
Number of paths to term: 12

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        part-ofadipose tissue development +
                                        part-ofbiomineral tissue development +
                                        is-abone development +
                                        is-abrain development +
                                        is-abronchus development +
                                        part-ofcarotid body glomus cell differentiation
                                        is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                is-abronchus cartilage development +
                                                part-ofcartilage condensation +
                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                part-ofcartilage morphogenesis +
                                                part-ofchondroblast differentiation
                                                part-ofchondrocyte differentiation +
                                                negatively-regulatesnegative regulation of cartilage development +
                                                positively-regulatespositive regulation of cartilage development +
                                                regulatesregulation of cartilage development +
                                                is-atrachea cartilage development +
                                        is-aembryonic organ development +
                                        part-ofendosperm development +
                                        is-aesophagus development
                                        is-afat body development +
                                        is-agall bladder development
                                        is-agenitalia development +
                                        is-agland development +
                                        is-agonad development +
                                        is-aheart development +
                                        is-ahematopoietic or lymphoid organ development +
                                        is-aimaginal disc development +
                                        is-akidney development +
                                        is-aliver development +
                                        is-alung development +
                                        part-ofmaintenance of organ identity +
                                        is-aMalpighian tubule development +
                                        part-ofmeristem development +
                                        part-ofmesenchyme development +
                                        part-ofmulticellular structure septum development +
                                        is-amuscle organ development +
                                        part-oforgan maturation +
                                        part-oforgan morphogenesis +
                                        is-aorgan regeneration +
                                        part-oforgan senescence +
                                        is-apancreas development +
                                        is-aplacenta development +
                                        is-apost-embryonic organ development +
                                        is-aproboscis development +
                                        is-arespiratory tube development +
                                        is-aroot development +
                                        is-asensory organ development +
                                        is-askin development +
                                        is-aspinal cord development +
                                        is-aspore-bearing organ development +
                                        part-ofstomach neuroendocrine cell differentiation +
                                        is-aswim bladder development +
                                        is-atrachea development +
                                        is-aureter development +
                                        is-aurethra development +
                                        is-aurinary bladder development
                                        is-auterus development +
                                        is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                part-ofadipose tissue development +
                                                part-ofbiomineral tissue development +
                                                is-abone development +
                                                is-abrain development +
                                                is-abronchus development +
                                                part-ofcarotid body glomus cell differentiation
                                                is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                        is-abronchus cartilage development +
                                                        part-ofcartilage condensation +
                                                        is-acartilage development involved in endochondral bone morphogenesis +
                                                        part-ofcartilage morphogenesis +
                                                        part-ofchondroblast differentiation
                                                        part-ofchondrocyte differentiation +
                                                        negatively-regulatesnegative regulation of cartilage development +
                                                        positively-regulatespositive regulation of cartilage development +
                                                        regulatesregulation of cartilage development +
                                                        is-atrachea cartilage development +
                                                is-aembryonic organ development +
                                                part-ofendosperm development +
                                                is-aesophagus development
                                                is-afat body development +
                                                is-agall bladder development
                                                is-agenitalia development +
                                                is-agland development +
                                                is-agonad development +
                                                is-aheart development +
                                                is-ahematopoietic or lymphoid organ development +
                                                is-aimaginal disc development +
                                                is-akidney development +
                                                is-aliver development +
                                                is-alung development +
                                                part-ofmaintenance of organ identity +
                                                is-aMalpighian tubule development +
                                                part-ofmeristem development +
                                                part-ofmesenchyme development +
                                                part-ofmulticellular structure septum development +
                                                is-amuscle organ development +
                                                part-oforgan maturation +
                                                part-oforgan morphogenesis +
                                                is-aorgan regeneration +
                                                part-oforgan senescence +
                                                is-apancreas development +
                                                is-aplacenta development +
                                                is-apost-embryonic organ development +
                                                is-aproboscis development +
                                                is-arespiratory tube development +
                                                is-aroot development +
                                                is-asensory organ development +
                                                is-askin development +
                                                is-aspinal cord development +
                                                is-aspore-bearing organ development +
                                                part-ofstomach neuroendocrine cell differentiation +
                                                is-aswim bladder development +
                                                is-atrachea development +
                                                is-aureter development +
                                                is-aurethra development +
                                                is-aurinary bladder development
                                                is-auterus development +
                                                is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-askeletal system development
                                                part-ofbone development +
                                                part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                        is-abronchus cartilage development +
                                                        part-ofcartilage condensation +
                                                        is-acartilage development involved in endochondral bone morphogenesis +
                                                        part-ofcartilage morphogenesis +
                                                        part-ofchondroblast differentiation
                                                        part-ofchondrocyte differentiation +
                                                        negatively-regulatesnegative regulation of cartilage development +
                                                        positively-regulatespositive regulation of cartilage development +
                                                        regulatesregulation of cartilage development +
                                                        is-atrachea cartilage development +
                                                is-aembryonic skeletal system development +
                                                part-ofskeletal system morphogenesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aconnective tissue development
                                                is-aadipose tissue development +
                                                is-abronchus cartilage development +
                                                is-acardiac skeleton development +
                                                part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                        is-abronchus cartilage development +
                                                        part-ofcartilage condensation +
                                                        is-acartilage development involved in endochondral bone morphogenesis +
                                                        part-ofcartilage morphogenesis +
                                                        part-ofchondroblast differentiation
                                                        part-ofchondrocyte differentiation +
                                                        negatively-regulatesnegative regulation of cartilage development +
                                                        positively-regulatespositive regulation of cartilage development +
                                                        regulatesregulation of cartilage development +
                                                        is-atrachea cartilage development +
                                                is-aglomerular mesangium development +
                                                is-agrowth plate cartilage development +
                                                is-akidney stroma development
                                                is-alung connective tissue development
                                                part-ofprostate gland stromal morphogenesis
                                                is-arenal capsule development +
                                                is-atendon development +
                                                is-atendon sheath development


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofadipose tissue development +
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        is-abronchus development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic organ development +
                                                        part-ofendosperm development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-aliver development +
                                                        is-alung development +
                                                        part-ofmaintenance of organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmeristem development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development +
                                                        is-amuscle organ development +
                                                        part-oforgan maturation +
                                                        part-oforgan morphogenesis +
                                                        is-aorgan regeneration +
                                                        part-oforgan senescence +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-aroot development +
                                                        is-asensory organ development +
                                                        is-askin development +
                                                        is-aspinal cord development +
                                                        is-aspore-bearing organ development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-askeletal system development
                                                        part-ofbone development +
                                                        part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic skeletal system development +
                                                        part-ofskeletal system morphogenesis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofadipose tissue development +
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        is-abronchus development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic organ development +
                                                        part-ofendosperm development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-aliver development +
                                                        is-alung development +
                                                        part-ofmaintenance of organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmeristem development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development +
                                                        is-amuscle organ development +
                                                        part-oforgan maturation +
                                                        part-oforgan morphogenesis +
                                                        is-aorgan regeneration +
                                                        part-oforgan senescence +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-aroot development +
                                                        is-asensory organ development +
                                                        is-askin development +
                                                        is-aspinal cord development +
                                                        is-aspore-bearing organ development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-askeletal system development
                                                        part-ofbone development +
                                                        part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic skeletal system development +
                                                        part-ofskeletal system morphogenesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofadipose tissue development +
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        is-abronchus development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic organ development +
                                                        part-ofendosperm development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-aliver development +
                                                        is-alung development +
                                                        part-ofmaintenance of organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmeristem development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development +
                                                        is-amuscle organ development +
                                                        part-oforgan maturation +
                                                        part-oforgan morphogenesis +
                                                        is-aorgan regeneration +
                                                        part-oforgan senescence +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-aroot development +
                                                        is-asensory organ development +
                                                        is-askin development +
                                                        is-aspinal cord development +
                                                        is-aspore-bearing organ development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-askeletal system development
                                                        part-ofbone development +
                                                        part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic skeletal system development +
                                                        part-ofskeletal system morphogenesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofadipose tissue development +
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        is-abronchus development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic organ development +
                                                        part-ofendosperm development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-aliver development +
                                                        is-alung development +
                                                        part-ofmaintenance of organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmeristem development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development +
                                                        is-amuscle organ development +
                                                        part-oforgan maturation +
                                                        part-oforgan morphogenesis +
                                                        is-aorgan regeneration +
                                                        part-oforgan senescence +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-aroot development +
                                                        is-asensory organ development +
                                                        is-askin development +
                                                        is-aspinal cord development +
                                                        is-aspore-bearing organ development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-askeletal system development
                                                        part-ofbone development +
                                                        part-ofcartilage development [GO:0051216] (165 genes, 287 annotations)
                                                                is-abronchus cartilage development +
                                                                part-ofcartilage condensation +
                                                                is-acartilage development involved in endochondral bone morphogenesis +
                                                                part-ofcartilage morphogenesis +
                                                                part-ofchondroblast differentiation
                                                                part-ofchondrocyte differentiation +
                                                                negatively-regulatesnegative regulation of cartilage development +
                                                                positively-regulatespositive regulation of cartilage development +
                                                                regulatesregulation of cartilage development +
                                                                is-atrachea cartilage development +
                                                        is-aembryonic skeletal system development +
                                                        part-ofskeletal system morphogenesis +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory