Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUB1
  • Mouse genes Sub1
  • Rat genes Sub1
  • Zfish genes sub1a,sub1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sub1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SUB1	IPI	UniProtKB:P53999	Human	PMID:16415882
Molecular Function	GO:0042802	identical protein binding	SUB1	IPI	UniProtKB:P53999	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	SUB1	IPI	UniProtKB:P53999	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SUB1	IPI	UniProtKB:P33240-1	Human	PMID:11389848
Molecular Function	GO:0005515	protein binding	SUB1	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SUB1	IPI	UniProtKB:P28288-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SUB1	IPI	UniProtKB:Q6P4D5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SUB1	IPI	UniProtKB:P03132	Human	PMID:9847329
Molecular Function	GO:0003723	RNA binding	SUB1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SUB1	HDA		Human	PMID:22681889
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Sub1	IDA		Mouse	PMID:18836447
Molecular Function	GO:0003697	single-stranded DNA binding	SUB1	IDA		Human	PMID:8062391
Molecular Function	GO:0003713	transcription coactivator activity	SUB1	IDA		Human	PMID:25308091
Molecular Function	GO:0003713	transcription coactivator activity	SUB1	IDA		Human	PMID:8062391
Cellular Component	GO:0070062	extracellular exosome	SUB1	HDA		Human	PMID:20458337
Cellular Component	GO:0005730	nucleolus	SUB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SUB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Sub1	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0005667	transcription regulator complex	SUB1	IDA		Human	PMID:8062391
Biological Process	GO:1905463	negative regulation of DNA duplex unwinding	SUB1	IDA		Human	PMID:16605275
Biological Process	GO:0051053	negative regulation of DNA metabolic process	SUB1	IDA		Human	PMID:28369605
Biological Process	GO:0032092	positive regulation of protein binding	SUB1	IPI	UniProtKB:P04486	Human	PMID:16605275
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	SUB1	IDA		Human	PMID:8062391
Biological Process	GO:0001111	RNA polymerase II promoter clearance	SUB1	IDA		Human	PMID:25308091
Biological Process	GO:0060395	SMAD protein signal transduction	Sub1	IDA		Mouse	PMID:23390484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern