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Sub1 Gene Detail
Summary
  • Symbol
    Sub1
  • Name
    SUB1 homolog (S. cerevisiae)
  • Synonyms
    P15, Pc4, Rpo2tc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104811
    NCBI Gene: 20024
  • Gene Overview
    MyGene.info: SUB1
Location & Maps
more
  • Sequence Map
    Chr15:11981339-11996983 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15645 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 5.90 cM, cytoband A2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SUB1, SUB1 homolog, transcriptional regulator
  • Vertebrate Orthologs
    12
  • Human Ortholog
    SUB1, SUB1 homolog, transcriptional regulator
    Orthology source: HGNC, HomoloGene
  • Synonyms
    p14, P15, PC4
  • Links
    NCBI Gene ID: 10923
    neXtProt AC: NX_P53999

  • Chr Location
    5p13.3; chr5:32585499-32604079 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    53
  • Gene trapped
    51
  • Targeted
    2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023586 VEGA Gene Model | MGI Sequence Detail 15645 C57BL/6J ±  kb
transcript OTTMUST00000057572 VEGA | MGI Sequence Detail 675 Not Applicable  
polypeptide OTTMUSP00000027772 VEGA | MGI Sequence Detail 127 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    175 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015810 activated RNA polymerase II transcriptional coactivator p15
  • InterPro Domains
    IPR009044 ssDNA-binding transcriptional regulator
    IPR003173 Transcriptional coactivator p15 (PC4)
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-28105, MGI:2146069
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:25189 Ballard DW, et al., Identification of a novel 9-kDa polypeptide from nuclear extracts. DNA binding properties, primary structure, and in vitro expression. J Biol Chem. 1988 Jun 15;263(17):8450-7
  • Latest
    J:195995 Redshaw N, et al., TGF-beta/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos. PLoS One. 2013;8(1):e55186

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory