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Sub1
Gene Detail
 Symbol
Name
ID
Sub1
SUB1 homolog (S. cerevisiae)
MGI:104811
Synonyms P15, Pc4, Rpo2tc1
Feature Type protein coding gene
Genetic Map
Chromosome 15
5.90 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:11981339-11996983 bp, - strand
From VEGA annotation of GRCm38

  15645 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38218  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: activated RNA polymerase II transcriptional coactivator p15
Gene Tree: Sub1

Human
homologs
Human Homolog SUB1, SUB1 homolog (S. cerevisiae)
NCBI Gene ID 10923
neXtProt AC  NX_P53999
Human Synonyms  p14, P15, PC4
Human Chr (Location)  5p13.3; chr5:32585499-32604079 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(53) : Gene trapped(51) Targeted(2)
Interactions
Sub1 interacts with 328 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-templated, ...
Component extracellular vesicular exosome, nucleolus, ...
Function DNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (168)    Tissues (159)    Images (5)
Theiler Stages: 11, 13, 15, 17, 19, 21, 22, 23, 27
Assay TypeResults
RNA in situ 166
RT-PCR 2
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023586 (Evidence)
Ensembl Gene ModelENSMUSG00000022205 (Evidence)
Entrez Gene20024 (Evidence)
DFCITC1571889, TC1617536, TC1634857
DoTSDT.40146671, DT.536285, DT.91395314
NIA Mouse Gene IndexU036014
Consensus CDS ProjectCCDS27387.1
International Mouse Knockout Project StatusSub1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023586 VEGA Gene Model | MGI Sequence Detail 15645 C57BL/6J ±  kb
transcript OTTMUST00000057571 VEGA | MGI Sequence Detail 3372 Not Applicable 
polypeptide OTTMUSP00000027771 VEGA | MGI Sequence Detail 127 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009044 ssDNA-binding transcriptional regulator
InterPro IPR003173 Transcriptional coactivator p15
Protein Ontology PR:000015810 activated RNA polymerase II transcriptional coactivator p15
References (Earliest) J:25189 Ballard DW, et al., Identification of a novel 9-kDa polypeptide from nuclear extracts. DNA binding properties, primary structure, and in vitro expression. J Biol Chem. 1988 Jun 15;263(17):8450-7
(Latest) J:195995 Redshaw N, et al., TGF-beta/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos. PLoS One. 2013;8(1):e55186
All references(44)
Other
accession IDs
MGD-MRK-28105, MGI:2146069

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory