Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STXBP3
  • Mouse genes Stxbp3
  • Rat genes Stxbp3
  • Zfish genes stxbp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stxbp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	STXBP3	IPI	UniProtKB:O00161	Human	PMID:12773094
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	UniProtKB:P63045|UniProtKB:Q08850	Mouse	MGI:MGI:6244867|PMID:19116655
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	UniProtKB:P70452	Mouse	MGI:MGI:5918742|PMID:21193638
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	UniProtKB:P70452	Mouse	MGI:MGI:6092969|PMID:17517664
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	UniProtKB:P70169	Mouse	MGI:MGI:4457249|PMID:17548353
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	UniProtKB:Q08850	Mouse	MGI:MGI:5613445|PMID:24469400
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	PR:P70452	Mouse	PMID:19188424
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	PR:P70452	Mouse	PMID:12297296
Molecular Function	GO:0005515	protein binding	Stxbp3	IPI	PR:P70452	Mouse	PMID:18535671
Molecular Function	GO:0044877	protein-containing complex binding	Stxbp3	IPI	RGD:3399|RGD:1309628	Rat	PMID:15707389|RGD:1642697
Molecular Function	GO:0019905	syntaxin binding	STXBP3	IPI	UniProtKB:P32856	Human	PMID:12773094
Molecular Function	GO:0019905	syntaxin binding	STXBP3	IPI	UniProtKB:Q12846	Human	PMID:15576373
Molecular Function	GO:0019905	syntaxin binding	Stxbp3	IPI	UniProtKB:P70452	Mouse	MGI:MGI:4457249|PMID:17548353
Molecular Function	GO:0019905	syntaxin binding	Stxbp3	IPI	UniProtKB:Q08850	Mouse	PMID:15690082
Molecular Function	GO:0019905	syntaxin binding	Stxbp3	IDA		Mouse	PMID:12297296
Molecular Function	GO:0019905	syntaxin binding	Stxbp3	IPI	RGD:621019	Rat	PMID:14759605|RGD:2306290
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp3	IDA		Rat	PMID:15563604|RGD:1302922
Cellular Component	GO:0016324	apical plasma membrane	Stxbp3	IDA		Mouse	PMID:18505797
Cellular Component	GO:0016324	apical plasma membrane	Stxbp3	IDA		Rat	PMID:14759605|RGD:2306290
Cellular Component	GO:0016323	basolateral plasma membrane	Stxbp3	IDA		Rat	PMID:14759605|RGD:2306290
Cellular Component	GO:0005829	cytosol	STXBP3	IDA		Human	PMID:18588921
Cellular Component	GO:0005829	cytosol	Stxbp3	IDA		Mouse	PMID:12297296
Cellular Component	GO:0005829	cytosol	Stxbp3	IDA		Mouse	PMID:12832401
Cellular Component	GO:0070062	extracellular exosome	STXBP3	HDA		Human	PMID:20458337
Cellular Component	GO:0045335	phagocytic vesicle	Stxbp3	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	STXBP3	IDA		Human	PMID:18588921
Cellular Component	GO:0005886	plasma membrane	Stxbp3	IPI	PR:P70452	Mouse	PMID:18535671
Cellular Component	GO:0005886	plasma membrane	Stxbp3	IDA		Mouse	PMID:18535671
Cellular Component	GO:0005886	plasma membrane	Stxbp3	IDA		Mouse	PMID:12832401
Cellular Component	GO:0005886	plasma membrane	Stxbp3	IDA		Mouse	PMID:12297296
Cellular Component	GO:0031091	platelet alpha granule	STXBP3	IDA		Human	PMID:12773094
Cellular Component	GO:0098793	presynapse	STXBP3	IDA		Human	PMID:27662481
Cellular Component	GO:0098793	presynapse	STXBP3	IMP		Human	PMID:27662481
Cellular Component	GO:0042581	specific granule	STXBP3	IDA		Human	PMID:18588921
Cellular Component	GO:0070820	tertiary granule	STXBP3	IDA		Human	PMID:18588921
Biological Process	GO:0007420	brain development	Stxbp3	IMP	MGI:MGI:3528591	Mouse	PMID:15690082
Biological Process	GO:0071346	cellular response to type II interferon	Stxbp3	IDA		Mouse	PMID:19144319
Biological Process	GO:0006887	exocytosis	Stxbp3	IMP	MGI:MGI:3573931	Mouse	PMID:19188424
Biological Process	GO:0030073	insulin secretion	Stxbp3	IMP	MGI:MGI:3573931	Mouse	PMID:19188424
Biological Process	GO:0001678	intracellular glucose homeostasis	Stxbp3	IDA		Mouse	PMID:12297296
Biological Process	GO:0001678	intracellular glucose homeostasis	Stxbp3	IMP		Mouse	PMID:12297296
Biological Process	GO:0045955	negative regulation of calcium ion-dependent exocytosis	STXBP3	IMP		Human	PMID:12649283
Biological Process	GO:0046325	negative regulation of glucose import	Stxbp3	IDA		Mouse	PMID:12297296
Biological Process	GO:0046325	negative regulation of glucose import	Stxbp3	IMP		Mouse	PMID:12297296
Biological Process	GO:0043312	neutrophil degranulation	STXBP3	IEP		Human	PMID:18588921
Biological Process	GO:0070527	platelet aggregation	STXBP3	IMP		Human	PMID:12773094
Biological Process	GO:0022615	protein to membrane docking	Stxbp3	IMP		Mouse	PMID:19188424
Biological Process	GO:0032868	response to insulin	Stxbp3	IMP	MGI:MGI:3528591	Mouse	PMID:15690082
Biological Process	GO:0032868	response to insulin	Stxbp3	IMP		Mouse	PMID:12297296
Biological Process	GO:0032868	response to insulin	Stxbp3	IDA		Mouse	PMID:12297296

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern