| GO term: | specific granule |
| Synonym: | secondary granule |
| GO id: | GO:0042581 |
| Definition: | Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. |
| Number of paths to term: | 21 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partintracellularintracellular partcytoplasmcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellularintracellular partcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellularintracellular partintracellular organellecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellular partcytoplasmcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellular partcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellular partintracellular organellecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcellcell partintracellular partintracellular organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellularintracellular partcytoplasmcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellularintracellular partcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellularintracellular partintracellular organellecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellular partcytoplasmcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellular partcytoplasmic partcytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellular partintracellular organellecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentcell partintracellular partintracellular organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentorganelleintracellular organellecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentorganelleintracellular organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentorganellemembrane-bounded organelleintracellular membrane-bounded organellecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentorganellevesiclecytoplasmic vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +cellular_componentorganellevesiclemembrane-bounded vesiclecytoplasmic membrane-bounded vesiclesecretory granuleacrosomal vesicle +azurophil granule +chromaffin granule +cortical granuledense core granule +insulin-responsive compartmentlamellar body +mucocystplatelet alpha granule +platelet dense granule +secretory granule lumen +secretory granule membrane +specific granule [GO:0042581] (10 genes, 10 annotations)specific granule lumenspecific granule membranetertiary granule +Weibel-Palade bodyzymogen granule +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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