Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SP4
  • Mouse genes Sp4
  • Rat genes Sp4
  • Zfish genes sp4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Sp4	IDA		Rat	PMID:15572681|RGD:1581116
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sp4	IDA		Rat	PMID:12746457|RGD:1581117
Molecular Function	GO:0042802	identical protein binding	SP4	IPI	UniProtKB:Q02446	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q75MZ5	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:A0A024R5S0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P14859	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P27658	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P86479	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q13444	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q16656	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q4G0S1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q75MZ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q8TAP4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q96Q77	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q9BTQ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:A0A0S2Z5G4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:B4DE54	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:A0A024R5S0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P14859-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P41970	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P52655	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q14119	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q5MJ09	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q5MJ10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q96Q77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SP4	IPI	UniProtKB:Q9HAT8	Human	PMID:32296183
Molecular Function	GO:0043565	sequence-specific DNA binding	SP4	IDA		Human	PMID:23332764
Cellular Component	GO:0005829	cytosol	SP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Sp4	IDA		Rat	PMID:15572681|RGD:1581116
Biological Process	GO:0008016	regulation of heart contraction	Sp4	IMP	MGI:MGI:2676622	Mouse	PMID:11007485
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	SP4	IDA		Human	PMID:7559627
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	SP4	IDA		Human	PMID:12560508

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern