Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHROOM2
  • Mouse genes Shroom2
  • Rat genes Shroom2
  • Zfish genes shroom2a,shroom2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shroom2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Molecular Function	GO:0051015	actin filament binding	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Molecular Function	GO:0051015	actin filament binding	Shroom2	IDA		Mouse	PMID:17666436
Molecular Function	GO:0008013	beta-catenin binding	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Molecular Function	GO:0005515	protein binding	SHROOM2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	Shroom2	IPI	PR:P97479	Mouse	PMID:17666436
Molecular Function	GO:0019904	protein domain specific binding	Shroom2	IPI	PR:P39447	Mouse	PMID:17666436
Molecular Function	GO:0019904	protein domain specific binding	Shroom2	IPI	PR:P97479	Mouse	PMID:17666436
Cellular Component	GO:0005912	adherens junction	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0043296	apical junction complex	Shroom2	IDA		Mouse	PMID:17666436
Cellular Component	GO:0016324	apical plasma membrane	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0005923	bicellular tight junction	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0005938	cell cortex	Shroom2	IDA		Mouse	PMID:17666436
Cellular Component	GO:0005911	cell-cell junction	Shroom2	IDA		Mouse	PMID:17666436
Cellular Component	GO:0030864	cortical actin cytoskeleton	SHROOM2	IDA		Human	PMID:16684770
Cellular Component	GO:0030864	cortical actin cytoskeleton	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0005737	cytoplasm	Shroom2	IDA		Mouse	PMID:17666436
Cellular Component	GO:0005856	cytoskeleton	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0070062	extracellular exosome	SHROOM2	HDA		Human	PMID:19056867
Cellular Component	GO:0043025	neuronal cell body	Shroom2	IDA		Mouse	PMID:17666436
Cellular Component	GO:0005886	plasma membrane	Shroom2	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Biological Process	GO:0016477	cell migration	Shroom2	IMP		Mouse	MGI:MGI:3690292|PMID:16684770
Biological Process	GO:0045217	cell-cell junction maintenance	Shroom2	IDA		Mouse	PMID:17666436
Biological Process	GO:0032438	melanosome organization	Shroom2	IMP		Mouse	MGI:MGI:3710716|PMID:16987870
Biological Process	GO:0030835	negative regulation of actin filament depolymerization	Shroom2	IDA		Mouse	PMID:17666436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern