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Shroom2 Gene Detail
Summary
  • Symbol
    Shroom2
  • Name
    shroom family member 2
  • Synonyms
    Apxl, Shrm2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107194
    NCBI Gene: 110380
Location & Maps
more
  • Sequence Map
    ChrX:152609992-152769465 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      159474 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM, cytoband F2-F3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SHROOM2, shroom family member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SHROOM2, shroom family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APXL, HSAPXL
  • Links
    NCBI Gene ID: 357
    neXtProt AC: NX_Q13796

  • Chr Location
    Xp22.3; chrX:9786402-9949443 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    30
  • Gene trapped
    28
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    12
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019337 VEGA Gene Model | MGI Sequence Detail 159474 C57BL/6J ±  kb
transcript OTTMUST00000046170 VEGA | MGI Sequence Detail 6997 Not Applicable  
polypeptide OTTMUSP00000020862 VEGA | MGI Sequence Detail 1481 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    669 from dbSNP Build 142
  • RFLP
    2
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35655, MGI:2443591
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:33821 Dinulos MB, et al., A new region of conservation is defined between human and mouse X chromosomes. Genomics. 1996 Jul 1;35(1):244-7
  • Latest
    J:220469 Grego-Bessa J, et al., Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory