Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETX
  • Mouse genes Setx
  • Rat genes Setx
  • Zfish genes setx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SETX	IPI	UniProtKB:Q7Z333	Human	PMID:24244371
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:O75533	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P11940	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P19338	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q16637	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q86U42	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P63279	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P63279	Human	PMID:24105744
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q06265	Human	PMID:24105744
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P63279	Human	PMID:24244371
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:P24928	Human	PMID:26700805
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q16637	Human	PMID:26700805
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:O75604-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q8N6K7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SETX	IPI	UniProtKB:Q9GZS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Setx	IPI	PR:Q9DBR1	Mouse	PMID:22767893
Molecular Function	GO:0005515	protein binding	Setx	IPI	PR:O54943	Mouse	PMID:22767893
Molecular Function	GO:0001147	transcription termination site sequence-specific DNA binding	SETX	IDA		Human	PMID:21700224
Cellular Component	GO:0030424	axon	SETX	IDA		Human	PMID:21576111
Cellular Component	GO:0005737	cytoplasm	SETX	IDA		Human	PMID:17562789
Cellular Component	GO:0005737	cytoplasm	SETX	IDA		Human	PMID:21576111
Cellular Component	GO:0030426	growth cone	SETX	IDA		Human	PMID:21576111
Cellular Component	GO:0045171	intercellular bridge	SETX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	SETX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000228	nuclear chromosome	SETX	IDA		Human	PMID:24105744
Cellular Component	GO:0005654	nucleoplasm	SETX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SETX	IDA		Human	PMID:17562789
Cellular Component	GO:0005634	nucleus	SETX	IDA		Human	PMID:17562789
Cellular Component	GO:0005634	nucleus	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0070301	cellular response to hydrogen peroxide	SETX	IDA		Human	PMID:17562789
Biological Process	GO:0034599	cellular response to oxidative stress	SETX	IDA		Human	PMID:17562789
Biological Process	GO:0071300	cellular response to retinoic acid	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0007623	circadian rhythm	Setx	IMP		Mouse	PMID:22767893
Biological Process	GO:0006974	DNA damage response	SETX	IDA		Human	PMID:17562789
Biological Process	GO:0006353	DNA-templated transcription termination	SETX	IMP		Human	PMID:26700805
Biological Process	GO:0006302	double-strand break repair	SETX	IDA		Human	PMID:17562789
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0000165	MAPK cascade	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0006376	mRNA splice site selection	SETX	IMP		Human	PMID:19515850
Biological Process	GO:0043066	negative regulation of apoptotic process	SETX	IDA		Human	PMID:21576111
Biological Process	GO:2000144	positive regulation of DNA-templated transcription initiation	SETX	IMP		Human	PMID:21700224
Biological Process	GO:0010976	positive regulation of neuron projection development	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0033120	positive regulation of RNA splicing	SETX	IMP		Human	PMID:19515850
Biological Process	GO:0060566	positive regulation of termination of DNA-templated transcription	SETX	IMP		Human	PMID:19515850
Biological Process	GO:2000806	positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled	SETX	IMP		Human	PMID:21700224
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SETX	IMP		Human	PMID:19515850
Biological Process	GO:0043491	protein kinase B signaling	SETX	IDA		Human	PMID:21576111
Biological Process	GO:0006369	termination of RNA polymerase II transcription	Setx	IMP		Mouse	PMID:22767893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern