Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPING1
  • Mouse genes Serping1
  • Rat genes Serping1
  • Zfish genes serping1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serping1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001848	complement binding	Serping1	IPI	UniProtKB:P04281	Mouse	PMID:9652403
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P27958:PRO_0000037573	Human	PMID:10570951
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:O00187	Human	PMID:10946292
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P48740	Human	PMID:10946292
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P0C045	Human	PMID:16237761
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P0C6X7:PRO_0000037310	Human	PMID:22046132
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P0C6X7:PRO_0000037320	Human	PMID:22046132
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:O82882	Human	PMID:22483117
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:O00187	Human	PMID:25359215
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P09871	Human	PMID:25359215
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:A0A7D5SLD3	Human	PMID:28484054
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:O00187	Human	PMID:28742139
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P00736	Human	PMID:28742139
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:P09871	Human	PMID:28742139
Molecular Function	GO:0005515	protein binding	SERPING1	IPI	UniProtKB:Q79GN7	Human	PMID:28742139
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPING1	IDA		Human	PMID:11527969
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Serping1	IDA		Mouse	PMID:9199246
Cellular Component	GO:0072562	blood microparticle	SERPING1	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPING1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPING1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Serping1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	SERPING1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SERPING1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	SERPING1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Serping1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Serping1	IDA		Mouse	PMID:9652403
Cellular Component	GO:0005615	extracellular space	Serping1	IDA		Rat	PMID:1505923|RGD:8661652
Biological Process	GO:0007568	aging	Serping1	IEP		Rat	PMID:21633715|RGD:7247626
Biological Process	GO:0001869	negative regulation of complement activation, lectin pathway	SERPING1	IDA		Human	PMID:10946292

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern