Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINA3
  • Mouse genes Serpina3n
  • Rat genes Serpina3n
  • Zfish genes serpina1,serpina1l,serpina7,si:ch211-186e20.7,zgc:113828,zgc:174259,zgc:174260
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpina3n

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q92876	Human	PMID:12709365
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q96KC8	Human	PMID:14668352
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UKR3	Human	PMID:14687906
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q96AX1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Cellular Component	GO:0072562	blood microparticle	SERPINA3	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINA3	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINA3	HDA		Human	PMID:28675934
Cellular Component	GO:0070062	extracellular exosome	SERPINA3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SERPINA3	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Serpina3n	IDA		Mouse	PMID:15795238
Cellular Component	GO:0005615	extracellular space	SERPINA3	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	SERPINA3	IDA		Human	PMID:25645918
Cellular Component	GO:0005615	extracellular space	Serpina3n	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Serpina3n	IDA		Rat	PMID:2439511|RGD:5147426
Biological Process	GO:0071320	cellular response to cAMP	Serpina3n	IEP		Rat	PMID:11578771|RGD:5147415
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Serpina3n	IEP		Rat	PMID:11578771|RGD:5147415
Biological Process	GO:0071347	cellular response to interleukin-1	Serpina3n	IEP		Rat	PMID:10547273|RGD:5147417
Biological Process	GO:0071354	cellular response to interleukin-6	Serpina3n	IEP		Rat	PMID:8611141|RGD:5147422
Biological Process	GO:0071346	cellular response to type II interferon	Serpina3n	IEP		Rat	PMID:7619083|RGD:5147424
Biological Process	GO:0006954	inflammatory response	Serpina3n	IEP		Rat	PMID:1694763|RGD:634091
Biological Process	GO:0009617	response to bacterium	Serpina3n	IEP		Mouse	PMID:23012479
Biological Process	GO:0034097	response to cytokine	Serpina3n	IDA		Mouse	PMID:15795238
Biological Process	GO:0032496	response to lipopolysaccharide	Serpina3n	IEP		Rat	PMID:12127095|RGD:5147408
Biological Process	GO:0043434	response to peptide hormone	Serpina3n	IDA		Mouse	PMID:15795238
Biological Process	GO:0034516	response to vitamin B6	Serpina3n	IEP		Rat	PMID:21462331|RGD:8662394

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern