Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SELENON
  • Mouse genes Selenon
  • Rat genes Selenon
  • Zfish genes selenon
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Selenon

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SELENON	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	SELENON	IPI	UniProtKB:P11716	Human	PMID:18713863
Molecular Function	GO:0005515	protein binding	SELENON	IPI	UniProtKB:P30957	Human	PMID:18713863
Molecular Function	GO:0005515	protein binding	SELENON	IPI	UniProtKB:Q9TS33	Human	PMID:18713863
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SELENON	IDA		Human	PMID:12700173
Biological Process	GO:0055074	calcium ion homeostasis	SELENON	IMP		Human	PMID:19557870
Biological Process	GO:0019722	calcium-mediated signaling	selenon	IMP		Zfish	PMID:18713863|ZFIN:ZDB-PUB-080826-31
Biological Process	GO:0071313	cellular response to caffeine	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0034599	cellular response to oxidative stress	Selenon	IGI	MGI:MGI:88110	Mouse	PMID:25452428
Biological Process	GO:0034599	cellular response to oxidative stress	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0034599	cellular response to oxidative stress	Selenon	IGI	MGI:MGI:1354385	Mouse	PMID:25452428
Biological Process	GO:0048286	lung alveolus development	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0007005	mitochondrion organization	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0033555	multicellular organismal response to stress	Selenon	IMP	MGI:MGI:5297977	Mouse	PMID:21858002
Biological Process	GO:0055001	muscle cell development	selenon	IMP		Zfish	PMID:18713863|ZFIN:ZDB-PUB-080826-31
Biological Process	GO:0060537	muscle tissue development	selenon	IMP		Zfish	PMID:17123513|ZFIN:ZDB-PUB-061205-15
Biological Process	GO:1902884	positive regulation of response to oxidative stress	SELENON	IMP		Human	PMID:19557870
Biological Process	GO:0014858	positive regulation of skeletal muscle cell proliferation	Selenon	IDA		Mouse	PMID:21131290
Biological Process	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	SELENON	IMP		Human	PMID:18713863
Biological Process	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	selenon	IMP		Zfish	PMID:18713863|ZFIN:ZDB-PUB-080826-31
Biological Process	GO:0003016	respiratory system process	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0014873	response to muscle activity involved in regulation of muscle adaptation	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0048741	skeletal muscle fiber development	Selenon	IMP		Mouse	PMID:23325319
Biological Process	GO:0048741	skeletal muscle fiber development	selenon	IMP	ZFIN:ZDB-MRPHLNO-070301-5	Zfish	PMID:17123513
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	Selenon	IMP	MGI:MGI:4946396	Mouse	PMID:21131290
Biological Process	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	Selenon	IMP		Mouse	MGI:MGI:4936779|PMID:21131290
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Selenon	IMP	MGI:MGI:4946396	Mouse	PMID:21131290

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern