Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCG2
  • Mouse genes Scg2
  • Rat genes Scg2
  • Zfish genes scg2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042056	chemoattractant activity	SCG2	IDA		Human	PMID:9473216
Molecular Function	GO:0005125	cytokine activity	SCG2	IDA		Human	PMID:14970115
Molecular Function	GO:0005515	protein binding	SCG2	IPI	UniProtKB:Q9UMX0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SCG2	IPI	UniProtKB:Q8WXE1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SCG2	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Cellular Component	GO:0031045	dense core granule	Scg2	IDA		Mouse	PMID:14622145
Cellular Component	GO:0005615	extracellular space	SCG2	IDA		Human	PMID:9473216
Cellular Component	GO:0098992	neuronal dense core vesicle	Scg2	IDA		Mouse	PMID:1918927
Cellular Component	GO:0098992	neuronal dense core vesicle	Scg2	IDA		Mouse	PMID:21044184
Cellular Component	GO:0030141	secretory granule	Scg2	IDA		Rat	PMID:21624661|RGD:8553933
Biological Process	GO:0001525	angiogenesis	SCG2	IDA		Human	PMID:14970115
Biological Process	GO:0001525	angiogenesis	Scg2	IDA		Mouse	MGI:MGI:3688376|PMID:14970115
Biological Process	GO:0048245	eosinophil chemotaxis	SCG2	IDA		Human	PMID:9473216
Biological Process	GO:0050930	induction of positive chemotaxis	SCG2	IDA		Human	PMID:9473216
Biological Process	GO:0035556	intracellular signal transduction	SCG2	IDA		Human	PMID:9473216
Biological Process	GO:0000165	MAPK cascade	SCG2	IDA		Human	PMID:14970115
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	SCG2	IDA		Human	PMID:14970115
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	SCG2	IDA		Human	PMID:14970115
Biological Process	GO:0050918	positive chemotaxis	SCG2	IDA		Human	PMID:9473216
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	SCG2	IDA		Human	PMID:14970115
Biological Process	GO:1903670	regulation of sprouting angiogenesis	scg2b	IMP	ZFIN:ZDB-GENO-190327-4	Zfish	PMID:29757409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern