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Scg2 Gene Detail
Summary
  • Symbol
    Scg2
  • Name
    secretogranin II
  • Synonyms
    Chgc, SgII
  • Feature Type
    protein coding gene
  • IDs
    MGI:103033
    NCBI Gene: 20254
  • Gene Overview
    MyGene.info: SCG2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:79434669-79440090 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 40.89 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103033
protein coding gene Chr1:79434669-79440120 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016204
protein coding gene Chr1:80207560-80213012 (-)
A/J MGP_AJ_G0016187
protein coding gene Chr1:77381535-77386987 (-)
AKR/J MGP_AKRJ_G0016144
protein coding gene Chr1:79507713-79513164 (-)
BALB/cJ MGP_BALBcJ_G0016142
protein coding gene Chr1:77455357-77460809 (-)
C3H/HeJ MGP_C3HHeJ_G0015972
protein coding gene Chr1:79869004-79874456 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016595
protein coding gene Chr1:83324087-83329538 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014315
protein coding gene Chr1:72717772-72723216 (-)
CAST/EiJ MGP_CASTEiJ_G0015557
protein coding gene Chr1:79232956-79238340 (-)
CBA/J MGP_CBAJ_G0015946
protein coding gene Chr1:86001402-86006853 (-)
DBA/2J MGP_DBA2J_G0016047
protein coding gene Chr1:76697153-76702604 (-)
FVB/NJ MGP_FVBNJ_G0016050
protein coding gene Chr1:75851405-75856857 (-)
LP/J MGP_LPJ_G0016119
protein coding gene Chr1:81361127-81366579 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016070
protein coding gene Chr1:89277645-89283096 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016642
protein coding gene Chr1:79617396-79622848 (-)
PWK/PhJ MGP_PWKPhJ_G0015343
protein coding gene Chr1:76131025-76136440 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015121
protein coding gene Chr1:78927373-78932749 (-)
WSB/EiJ MGP_WSBEiJ_G0015618
protein coding gene Chr1:79414163-79419614 (-)



Homology
more
  • Human Ortholog
    SCG2, secretogranin II
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCG2, secretogranin II
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CHGC, EM66, SgII, SN
  • Links
    NCBI Gene ID: 7857
    neXtProt AC: NX_P13521
    UniProt: P13521

  • Chr Location
    2q36.1; chr2:223596940-223602499 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2591
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SCG2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20254 NCBI Gene Model | MGI Sequence Detail 5422 C57BL/6J ±  kb
transcript NM_009129 RefSeq | MGI Sequence Detail 2485 C57BL/6  
polypeptide Q03517 UniProt | EBI | MGI Sequence Detail 617 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    Genomic 1
    cDNA 57
    Primer pair 4
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-1971, MGD-MRK-23870
References
more
  • Summaries
    All 54
    Developmental Gene Expression 13
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:227048 Kim HJ, et al., REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. J Neurosci. 2015 Nov 4;35(44):14872-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory