Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RREB1
  • Mouse genes Rreb1
  • Rat genes Rreb1
  • Zfish genes rreb1a,rreb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rreb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	RREB1	IDA		Human	PMID:8816445
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rreb1	IDA		Mouse	PMID:21159816
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	RREB1	IMP		Human	PMID:20133935
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	RREB1	IDA		Human	PMID:8816445
Cellular Component	GO:0070062	extracellular exosome	RREB1	HDA		Human	PMID:19056867
Cellular Component	GO:0001650	fibrillar center	RREB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	RREB1	IDA		Human	GO_REF:0000052
Biological Process	GO:0006351	DNA-templated transcription	Rreb1	IDA		Mouse	MGI:MGI:4849556|PMID:21159816
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Rreb1	IDA		Mouse	PMID:21159816
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	RREB1	IMP		Human	PMID:20133935
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rreb1	IMP		Mouse	MGI:MGI:5613471|PMID:20133935
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	Rreb1	IMP		Mouse	MGI:MGI:5812817|PMID:27923061
Biological Process	GO:0010634	positive regulation of epithelial cell migration	RREB1	IMP		Human	PMID:18394891
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	RREB1	IMP		Human	PMID:18394891
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	RREB1	IMP		Human	PMID:18394891
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	RREB1	IMP		Human	PMID:18394891
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RREB1	IDA		Human	PMID:8816445
Biological Process	GO:1903691	positive regulation of wound healing, spreading of epidermal cells	RREB1	IMP		Human	PMID:18394891
Biological Process	GO:0006355	regulation of DNA-templated transcription	Rreb1	IDA		Mouse	MGI:MGI:4849556|PMID:21159816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern