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Rreb1 Gene Detail
Summary
  • Symbol
    Rreb1
  • Name
    ras responsive element binding protein 1
  • Synonyms
    1110037N09Rik, B930013M22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443664
    NCBI Gene: 68750
  • Gene Overview
    MyGene.info: RREB1
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:37778400-37952005 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 17.70 cM, cytoband A5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    947 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443664
protein coding gene Chr13:37778380-37952005 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020466
protein coding gene Chr13:36072702-36260718 (+)
A/J MGP_AJ_G0020420
protein coding gene Chr13:34944372-35121408 (+)
AKR/J MGP_AKRJ_G0020398
protein coding gene Chr13:35871115-36047774 (+)
BALB/cJ MGP_BALBcJ_G0020416
protein coding gene Chr13:35043876-35220276 (+)
C3H/HeJ MGP_C3HHeJ_G0020215
protein coding gene Chr13:35693773-35876999 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020849
protein coding gene Chr13:37256013-37444021 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018436
protein coding gene Chr13:33124048-33301691 (+)
CAST/EiJ MGP_CASTEiJ_G0019730
protein coding gene Chr13:35450210-35636893 (+)
CBA/J MGP_CBAJ_G0020176
protein coding gene Chr13:38831799-39034071 (+)
DBA/2J MGP_DBA2J_G0020298
protein coding gene Chr13:34466860-34642344 (+)
FVB/NJ MGP_FVBNJ_G0020277
protein coding gene Chr13:34004073-34182086 (+)
LP/J MGP_LPJ_G0020373
protein coding gene Chr13:36320775-36503421 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020307
protein coding gene Chr13:38961719-39146899 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020892
protein coding gene Chr13:35435840-35620340 (+)
PWK/PhJ MGP_PWKPhJ_G0019485
protein coding gene Chr13:34579493-34763271 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019316
protein coding gene Chr13:34096050-34279349 (+)
WSB/EiJ MGP_WSBEiJ_G0019792
protein coding gene Chr13:35783991-35969187 (+)



Homology
more
  • Human Ortholog
    RREB1, ras responsive element binding protein 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    RREB1, ras responsive element binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FINB, HNT, LZ321, RREB-1, Zep-1
  • Links
    NCBI Gene ID: 6239
    neXtProt AC: NX_Q92766
    UniProt: Q92766

  • Chr Location
    6p24.3; chr6:7107597-7251980 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2218
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RREB1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039087 Ensembl Gene Model | MGI Sequence Detail 173606 C57BL/6J ±  kb
    transcript ENSMUST00000037232 Ensembl | MGI Sequence Detail 8395 Not Applicable  
    polypeptide ENSMUSP00000049265 Ensembl | MGI Sequence Detail 1754 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1916000, MGI:2145160
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory