Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ror2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ROR2
- Mouse genes Ror2
- Rat genes Ror2
- Zfish genes ror2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ror2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005109	frizzled binding	Ror2	IPI	UniProtKB:Q9JIP6	Mouse	MGI:MGI:3042073\|PMID:12839624
Molecular Function	GO:0005109	frizzled binding	Ror2	IPI	PR:Q61089	Mouse	PMID:18606138
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ROR2	IPI	UniProtKB:O43318	Human	PMID:18762249
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Ror2	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:6148351\|PMID:18762249
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q5HYA8	Human	PMID:26035863
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O43186	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:A1KXE4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:A4D0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O14503	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O43186	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O43711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O95231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:O95416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:P35548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:P53539	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:P78337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q03060-25	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q16633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q2M1V0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q3SYF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q5SWW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q6P1W5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q6ZVD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q8IUC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q8N813	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q9NP73-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROR2	IPI	UniProtKB:Q9UPM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ror2	IPI	UniProtKB:Q9DCP9	Mouse	MGI:MGI:6148351\|PMID:18762249
Molecular Function	GO:0005515	protein binding	Ror2	IPI	UniProtKB:Q61062	Mouse	MGI:MGI:5466648\|PMID:23109420
Molecular Function	GO:0005515	protein binding	Ror2	IPI	PR:Q9JIP6	Mouse	PMID:12839624
Molecular Function	GO:0005515	protein binding	Ror2	IPI	PR:P22725	Mouse	PMID:12839624
Molecular Function	GO:0005515	protein binding	Ror2	IPI	PR:Q9D1D6	Mouse	PMID:18606138
Molecular Function	GO:0046982	protein heterodimerization activity	ror2	IPI	ZFIN:ZDB-GENE-990603-12	Zfish	PMID:24928507
Molecular Function	GO:0017147	Wnt-protein binding	ROR2	IPI	UniProtKB:Q9H1J7	Human	PMID:19486338
Molecular Function	GO:0017147	Wnt-protein binding	Ror2	IPI	PR:P22725	Mouse	PMID:18606138
Cellular Component	GO:0009986	cell surface	Ror2	IDA		Rat	PMID:15095375\|RGD:11537371
Cellular Component	GO:0005737	cytoplasm	Ror2	IDA		Rat	PMID:15095375\|RGD:11537371
Cellular Component	GO:0030425	dendrite	Ror2	IDA		Rat	PMID:25825749\|RGD:11537351
Cellular Component	GO:0098978	glutamatergic synapse	Ror2	IDA		Rat	PMID:26003414\|RGD:11344299
Cellular Component	GO:0098978	glutamatergic synapse	Ror2	IMP		Rat	PMID:26003414\|RGD:11344299
Cellular Component	GO:0098978	glutamatergic synapse	Ror2	IDA		Rat	PMID:26311509\|RGD:11353570
Cellular Component	GO:0098978	glutamatergic synapse	Ror2	IMP		Rat	PMID:26311509\|RGD:11353570
Cellular Component	GO:0005874	microtubule	Ror2	IDA		Rat	PMID:15095375\|RGD:11537371
Cellular Component	GO:0043025	neuronal cell body	Ror2	IDA		Rat	PMID:25825749\|RGD:11537351
Cellular Component	GO:0098794	postsynapse	Ror2	IDA		Rat	PMID:26003414\|RGD:11344299
Biological Process	GO:0014002	astrocyte development	Ror2	IDA		Rat	PMID:15095375\|RGD:11537371
Biological Process	GO:0030509	BMP signaling pathway	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0030282	bone mineralization	Ror2	IEP		Rat	PMID:23337931\|RGD:11537369
Biological Process	GO:0001502	cartilage condensation	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:14745966
Biological Process	GO:0045165	cell fate commitment	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0002062	chondrocyte differentiation	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:14745966
Biological Process	GO:0060027	convergent extension involved in gastrulation	ror2	IGI	ZFIN:ZDB-MRPHLNO-141201-20	Zfish	PMID:25183869
Biological Process	GO:0042733	embryonic digit morphogenesis	Ror2	IGI	MGI:MGI:96533	Mouse	PMID:20660756
Biological Process	GO:0042733	embryonic digit morphogenesis	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0042733	embryonic digit morphogenesis	Ror2	IMP	MGI:MGI:2386954	Mouse	PMID:20660756
Biological Process	GO:0030538	embryonic genitalia morphogenesis	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:14745966
Biological Process	GO:0042472	inner ear morphogenesis	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:18606138
Biological Process	GO:0007254	JNK cascade	Ror2	IDA		Mouse	PMID:12839624
Biological Process	GO:1905517	macrophage migration	Ror2	IMP		Rat	PMID:25749876\|RGD:11537353
Biological Process	GO:0030539	male genitalia development	Ror2	IEP		Rat	PMID:23895974\|RGD:11537370
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ror2	IDA		Rat	PMID:26311509\|RGD:11353570
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ror2	IMP		Rat	PMID:26311509\|RGD:11353570
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Ror2	IGI	MGI:MGI:98958	Mouse	PMID:16602827
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Ror2	IDA		Mouse	MGI:MGI:4835141\|PMID:18215320
Biological Process	GO:0030335	positive regulation of cell migration	ROR2	IDA		Human	PMID:19486338
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ror2	IDA		Mouse	MGI:MGI:4835141\|PMID:18215320
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Ror2	IMP		Rat	PMID:25825749\|RGD:11537351
Biological Process	GO:0045651	positive regulation of macrophage differentiation	Ror2	IMP		Rat	PMID:25749876\|RGD:11537353
Biological Process	GO:1900020	positive regulation of protein kinase C activity	Ror2	IMP		Rat	PMID:25825749\|RGD:11537351
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Ror2	IMP		Rat	PMID:25825749\|RGD:11537351
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0099175	regulation of postsynapse organization	Ror2	IDA		Rat	PMID:26003414\|RGD:11344299
Biological Process	GO:0099175	regulation of postsynapse organization	Ror2	IMP		Rat	PMID:26003414\|RGD:11344299
Biological Process	GO:0150045	regulation of synaptic signaling by nitric oxide	Ror2	IDA		Rat	PMID:26311509\|RGD:11353570
Biological Process	GO:0150045	regulation of synaptic signaling by nitric oxide	Ror2	IMP		Rat	PMID:26311509\|RGD:11353570
Biological Process	GO:0007165	signal transduction	ROR2	IMP		Human	PMID:19486338
Biological Process	GO:0001501	skeletal system development	Ror2	IMP	MGI:MGI:2386954	Mouse	PMID:10700181
Biological Process	GO:0060395	SMAD protein signal transduction	Ror2	IMP	MGI:MGI:2386954	Mouse	PMID:20660756
Biological Process	GO:0060395	SMAD protein signal transduction	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0007224	smoothened signaling pathway	Ror2	IMP	MGI:MGI:3793279	Mouse	PMID:20660756
Biological Process	GO:0001756	somitogenesis	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:14745966
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	Ror2	IPI	PR:Q9JIP6	Mouse	PMID:12839624
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	Ror2	IPI	PR:P22725	Mouse	PMID:12839624
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	Ror2	IMP	MGI:MGI:2183225	Mouse	PMID:18606138

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.