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Gene Ontology Browser
Term Detail
GO term:Wnt signaling pathway, calcium modulating pathway
Synonym: frizzled-2 signaling pathway
Synonym: frizzled-2 signalling pathway
Synonym: non-canonical Wnt signaling pathway
Synonym: Wnt-activated signaling pathway, calcium modulating pathway
Synonym: Wnt receptor signaling pathway, calcium modulating pathway
GO id:GO:0007223
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-anon-canonical Wnt signaling pathway
                                                                        negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                        is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                        is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                        positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                        regulatesregulation of non-canonical Wnt signaling pathway +
                                                                        is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                                negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                        is-aWnt signaling pathway, planar cell polarity pathway +
                                                                        is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-anon-canonical Wnt signaling pathway
                                                                        negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                        is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                        is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                        positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                        regulatesregulation of non-canonical Wnt signaling pathway +
                                                                        is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                                negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                        is-aWnt signaling pathway, planar cell polarity pathway +
                                                                        is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-anon-canonical Wnt signaling pathway
                                                                negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                regulatesregulation of non-canonical Wnt signaling pathway +
                                                                is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                        negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                        regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                is-aWnt signaling pathway, planar cell polarity pathway +
                                                                is-aWnt signaling pathway, regulating spindle positioning


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-anon-canonical Wnt signaling pathway
                                                                        negatively-regulatesnegative regulation of non-canonical Wnt signaling pathway +
                                                                        is-anon-canonical Wnt signaling pathway involved in heart development +
                                                                        is-anon-canonical Wnt signaling pathway via MAPK cascade +
                                                                        positively-regulatespositive regulation of non-canonical Wnt signaling pathway +
                                                                        regulatesregulation of non-canonical Wnt signaling pathway +
                                                                        is-aWnt signaling pathway, calcium modulating pathway [GO:0007223] (6 genes, 9 annotations)
                                                                                negatively-regulatesnegative regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                positively-regulatespositive regulation of Wnt signaling pathway, calcium modulating pathway
                                                                                regulatesregulation of Wnt signaling pathway, calcium modulating pathway +
                                                                        is-aWnt signaling pathway, planar cell polarity pathway +
                                                                        is-aWnt signaling pathway, regulating spindle positioning


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory