Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF135
  • Mouse genes Rnf135
  • Rat genes Rnf135
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf135

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	RNF135	IPI	UniProtKB:Q8IUD6	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RNF135	IPI	UniProtKB:Q8IUD6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:O95786	Human	PMID:19017631
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:Q9UBT7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF135	IPI	UniProtKB:Q9UBT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rnf135	IPI	PR:Q9D828	Mouse	PMID:11591653
Molecular Function	GO:0043021	ribonucleoprotein complex binding	RNF135	IPI	UniProtKB:Q15366	Human	PMID:19881509
Molecular Function	GO:0043021	ribonucleoprotein complex binding	RNF135	IDA		Human	PMID:31006531
Molecular Function	GO:0039552	RIG-I binding	RNF135	IPI	UniProtKB:O95786	Human	PMID:23950712
Molecular Function	GO:0039552	RIG-I binding	RNF135	IPI	UniProtKB:O95786	Human	PMID:31006531
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF135	IDA		Human	PMID:31006531
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF135	EXP		Human	PMID:17392790
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF135	EXP		Human	PMID:19017631
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF135	EXP		Human	PMID:19484123
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF135	IDA		Human	PMID:19484123
Cellular Component	GO:0005737	cytoplasm	RNF135	IDA		Human	PMID:19484123
Cellular Component	GO:0010494	cytoplasmic stress granule	RNF135	IDA		Human	PMID:23950712
Cellular Component	GO:1990904	ribonucleoprotein complex	RNF135	IDA		Human	PMID:31006531
Biological Process	GO:0140374	antiviral innate immune response	RNF135	IMP		Human	PMID:28469175
Biological Process	GO:0140374	antiviral innate immune response	RNF135	IMP		Human	PMID:31006531
Biological Process	GO:0140374	antiviral innate immune response	Rnf135	IMP		Mouse	MGI:MGI:6155526|PMID:23950712
Biological Process	GO:0140374	antiviral innate immune response	Rnf135	IMP		Mouse	MGI:MGI:6152590|PMID:21147464
Biological Process	GO:0010994	free ubiquitin chain polymerization	RNF135	IDA		Human	PMID:31006531
Biological Process	GO:0032728	positive regulation of interferon-beta production	RNF135	IMP		Human	PMID:19017631
Biological Process	GO:0051260	protein homooligomerization	RNF135	IDA		Human	PMID:31006531
Biological Process	GO:0070534	protein K63-linked ubiquitination	RNF135	IDA		Human	PMID:31006531
Biological Process	GO:0000209	protein polyubiquitination	RNF135	IDA		Human	PMID:31006531
Biological Process	GO:0000209	protein polyubiquitination	Rnf135	IGI	UniProtKB:Q8IUD6	Mouse	MGI:MGI:6152590|PMID:21147464
Biological Process	GO:0016567	protein ubiquitination	RNF135	IDA		Human	PMID:19017631
Biological Process	GO:0016567	protein ubiquitination	RNF135	IDA		Human	PMID:19484123
Biological Process	GO:0045088	regulation of innate immune response	RNF135	IMP		Human	PMID:19017631
Biological Process	GO:0039529	RIG-I signaling pathway	RNF135	IDA		Human	PMID:23950712
Biological Process	GO:0039529	RIG-I signaling pathway	RNF135	IMP		Human	PMID:28469175
Biological Process	GO:0039529	RIG-I signaling pathway	RNF135	IMP		Human	PMID:31006531
Biological Process	GO:0039529	RIG-I signaling pathway	Rnf135	IMP		Mouse	MGI:MGI:6152590|PMID:21147464
Biological Process	GO:0039529	RIG-I signaling pathway	Rnf135	IMP		Mouse	MGI:MGI:6377978|PMID:28469175
Biological Process	GO:0039529	RIG-I signaling pathway	Rnf135	IGI	UniProtKB:Q8IUD6	Mouse	MGI:MGI:6152590|PMID:21147464

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern