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Rnf135
Gene Detail
 Symbol
Name
ID
Rnf135
ring finger protein 135
MGI:1919206
Synonyms 0610037N03Rik, 2410006N06Rik, MGC13061, U 2-3-0
Feature Type protein coding gene
Genetic Map
Chromosome 11
47.59 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:80183851-80199757 bp, + strand
From VEGA annotation of GRCm38

  15907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12427  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Rnf135

Human
homologs
Human Homolog RNF135, ring finger protein 135
NCBI Gene ID 84282
neXtProt AC  NX_Q8IUD6
Human Synonyms  MMFD, REUL, Riplet
Human Chr (Location)  17q11.2; chr17:30958292-30999911 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RNF135
Mutations,
alleles, and
phenotypes
All mutations/alleles(52) : Gene trapped(52)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rnf135 interacts with 104 markers (Mir15a, Mir30a, Mir30d, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process immune system process, innate immune response, ...
Component cytoplasm
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (77)    Tissues (56)    Images (5)
Theiler Stages: 10, 13, 16, 17, 20, 21, 22, 23, 28
Assay TypeResults
RNA in situ 69
RT-PCR 8
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000000220 (Evidence)
Ensembl Gene ModelENSMUSG00000020707 (Evidence)
Entrez Gene71956 (Evidence)
DFCITC1581413, TC1595619
DoTSDT.485307
NIA Mouse Gene IndexU013049
EC6.3.2.-
Consensus CDS ProjectCCDS25129.1
International Mouse Knockout Project StatusRnf135
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000220 VEGA Gene Model | MGI Sequence Detail 15907 C57BL/6J ±  kb
transcript OTTMUST00000000651 VEGA | MGI Sequence Detail 1984 Not Applicable 
polypeptide OTTMUSP00000000286 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001870 B30.2/SPRY domain
InterPro IPR003879 Butyrophylin-like
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR003877 SPla/RYanodine receptor SPRY
InterPro IPR006574 SPRY-associated
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000014083 E3 ubiquitin-protein ligase RNF135
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(35)
Other
accession IDs
MGI:1915638

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory