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Rnf135 Gene Detail
Summary
  • Symbol
    Rnf135
  • Name
    ring finger protein 135
  • Synonyms
    0610037N03Rik, 2410006N06Rik, MGC13061, U 2-3-0
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919206
    NCBI Gene: 71956
  • Gene Overview
    MyGene.info: RNF135
Location & Maps
more
  • Sequence Map
    Chr11:80183851-80199757 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15907 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 47.59 cM, cytoband B5
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RNF135, ring finger protein 135
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RNF135, ring finger protein 135
    Orthology source: HomoloGene, HGNC
  • Synonyms
    L13, MMFD, REUL, Riplet
  • Links
    NCBI Gene ID: 84282
    neXtProt AC: NX_Q8IUD6

  • Chr Location
    17q11.2; chr17:30958921-30999911 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human RNF135 associations

Human Disease Mouse Models
       Macrocephaly, Macrosomia, and Facial Dysmorphism Syndrome; MMFD   OMIM: 614192
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    54
  • Chemically induced (other)
    1
  • Gene trapped
    52
  • Targeted
    1
  • Genomic Mutations
    2 involving Rnf135
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000220 VEGA Gene Model | MGI Sequence Detail 15907 C57BL/6J ±  kb
transcript OTTMUST00000000651 VEGA | MGI Sequence Detail 1984 Not Applicable  
polypeptide OTTMUSP00000000286 VEGA | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    101 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915638
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory